海峡药学
海峽藥學
해협약학
STRAIT PHARMACEUTICAL JOURNAL
2014年
3期
22-24
,共3页
颈痛灵乳膏%羟基红花黄色素A%高效液相色谱法%正交试验%提取工艺
頸痛靈乳膏%羥基紅花黃色素A%高效液相色譜法%正交試驗%提取工藝
경통령유고%간기홍화황색소A%고효액상색보법%정교시험%제취공예
Jingtongling Cream%Hydroxysafflor yellow A%HPLC%Orthogonal test%Extraction techonology
目的：优选颈痛灵乳膏的最佳提取工艺。方法采用高效液相色谱法.以红花中羟基红花黄色素 A为指标.正交试验设计考察乙醇浓度、溶媒用量、提取时间、提取次数对提取效果的影响。结果颈痛灵乳膏的提取工艺确定为A2 B2 C3 D2，即加入10倍量70％乙醇回流提取2次，每次提取时间为1.5h。结论此工艺对羟基红花黄色素A的提取率高，稳定性好，适合工业化生产。
目的：優選頸痛靈乳膏的最佳提取工藝。方法採用高效液相色譜法.以紅花中羥基紅花黃色素 A為指標.正交試驗設計攷察乙醇濃度、溶媒用量、提取時間、提取次數對提取效果的影響。結果頸痛靈乳膏的提取工藝確定為A2 B2 C3 D2，即加入10倍量70％乙醇迴流提取2次，每次提取時間為1.5h。結論此工藝對羥基紅花黃色素A的提取率高，穩定性好，適閤工業化生產。
목적：우선경통령유고적최가제취공예。방법채용고효액상색보법.이홍화중간기홍화황색소 A위지표.정교시험설계고찰을순농도、용매용량、제취시간、제취차수대제취효과적영향。결과경통령유고적제취공예학정위A2 B2 C3 D2，즉가입10배량70％을순회류제취2차，매차제취시간위1.5h。결론차공예대간기홍화황색소A적제취솔고，은정성호，괄합공업화생산。
OBJECTIVE To optimize the extraction techonology of Jingtongling Cream.METHODS With the content of hydroxysafflor yellow A in Carthamus Tinctorius L as index ,the optimum extraction condition for the etha-nol concentration,volume,extractoin time and times were selected by orthogonal design.The content of Safflor Yellow A were determind by HPLC.RESULTS The certain extraction techonology of Jingtong Ling Cream was A 2 B3 C3 D2 , The addition of 10 times of 70% ethanol was added and extracted 3 times.Extraction time was 1.5 hours.CONCLUSION This process has high rate for the hydroxysafflor yellow A extraction ,good stability ,suitable for industrial production.
