内蒙古医学杂志
內矇古醫學雜誌
내몽고의학잡지
INNER MONGOLIA MEDICAL JOURNAL
2013年
12期
1455-1458
,共4页
糖尿病%CA199
糖尿病%CA199
당뇨병%CA199
目的:探讨糖尿病患者血清糖类抗原199(CA199)的浓度及其与血脂、肾功和血糖的相关性.方法:选取60例糖尿病患者及30例健康对照组,用化学发光法检测CA199浓度;用己糖激酶法检测空腹血糖浓度;用离子交换高效液相色谱法检测糖化血红蛋白;用日立7600检测血清TG、TC、HDL、LDL、VLDL、BUN、Cr、Cys C及UA的浓度.结果:糖尿病患者U-mAlb＞1.90 mg/dl组CA199水平显著高于糖尿病患者U-rnAlb＜1.90 mg/dl组和健康对照组(P =0.05、P=0.001);糖尿病患者血清CA199的水平与空腹血糖及糖化血红蛋白的水平呈显著正相关(r =0.529,P＜0.001;r=0.567,P＜ 0.001);糖尿病患者血清CA199的水平与血清TC及LDL的水平呈显著正相关(r=0.376,P=0.001;r =0.296,P=0.008);糖尿病患者血清CA199的水平与血清BUN水平呈显著正相关(r=0.324,P=0.021);糖尿病患者血清CA199的水平与Cr及UA水平呈显著负相关(r=-0.314,P=0.025;r=-0.371,P=0.007).结论:糖尿病患者血清CA199浓度升高,且与疾病进展有一定相关性.
目的:探討糖尿病患者血清糖類抗原199(CA199)的濃度及其與血脂、腎功和血糖的相關性.方法:選取60例糖尿病患者及30例健康對照組,用化學髮光法檢測CA199濃度;用己糖激酶法檢測空腹血糖濃度;用離子交換高效液相色譜法檢測糖化血紅蛋白;用日立7600檢測血清TG、TC、HDL、LDL、VLDL、BUN、Cr、Cys C及UA的濃度.結果:糖尿病患者U-mAlb＞1.90 mg/dl組CA199水平顯著高于糖尿病患者U-rnAlb＜1.90 mg/dl組和健康對照組(P =0.05、P=0.001);糖尿病患者血清CA199的水平與空腹血糖及糖化血紅蛋白的水平呈顯著正相關(r =0.529,P＜0.001;r=0.567,P＜ 0.001);糖尿病患者血清CA199的水平與血清TC及LDL的水平呈顯著正相關(r=0.376,P=0.001;r =0.296,P=0.008);糖尿病患者血清CA199的水平與血清BUN水平呈顯著正相關(r=0.324,P=0.021);糖尿病患者血清CA199的水平與Cr及UA水平呈顯著負相關(r=-0.314,P=0.025;r=-0.371,P=0.007).結論:糖尿病患者血清CA199濃度升高,且與疾病進展有一定相關性.
목적:탐토당뇨병환자혈청당류항원199(CA199)적농도급기여혈지、신공화혈당적상관성.방법:선취60례당뇨병환자급30례건강대조조,용화학발광법검측CA199농도;용기당격매법검측공복혈당농도;용리자교환고효액상색보법검측당화혈홍단백;용일립7600검측혈청TG、TC、HDL、LDL、VLDL、BUN、Cr、Cys C급UA적농도.결과:당뇨병환자U-mAlb＞1.90 mg/dl조CA199수평현저고우당뇨병환자U-rnAlb＜1.90 mg/dl조화건강대조조(P =0.05、P=0.001);당뇨병환자혈청CA199적수평여공복혈당급당화혈홍단백적수평정현저정상관(r =0.529,P＜0.001;r=0.567,P＜ 0.001);당뇨병환자혈청CA199적수평여혈청TC급LDL적수평정현저정상관(r=0.376,P=0.001;r =0.296,P=0.008);당뇨병환자혈청CA199적수평여혈청BUN수평정현저정상관(r=0.324,P=0.021);당뇨병환자혈청CA199적수평여Cr급UA수평정현저부상관(r=-0.314,P=0.025;r=-0.371,P=0.007).결론:당뇨병환자혈청CA199농도승고,차여질병진전유일정상관성.
