CAJ | 학술논문

目的：探讨ADC值对肺部良恶性结节、肿块样病变诊断的应用价值。方法：将行胸部磁共振检查的肺内直径1 cm以上的结节、肿块样病变的57例作为研究对象，全部病例均经病理证实。对病变进行ADC值定量分析，比较肺良恶性病变ADC值的差异。结果：恶性病变组ADC值为（1．26±0．32×10-3 mm2/s，良性病变组ADC值为（1．82±0．41）×10-3 mm2/s，良恶性病变组ADC值的差异有高度统计学意义（P＜0．001），诊断阈值为1．49×10-3 mm2/s。结论DWI实现了肺部病变ADC值的定量分析，有望成为肺部良恶性病变鉴别诊断的一种新方法。
목적：탐토ADC치대폐부량악성결절、종괴양병변진단적응용개치。방법：장행흉부자공진검사적폐내직경1 cm이상적결절、종괴양병변적57례작위연구대상，전부병례균경병리증실。대병변진행ADC치정량분석，비교폐량악성병변ADC치적차이。결과：악성병변조ADC치위（1．26±0．32×10-3 mm2/s，량성병변조ADC치위（1．82±0．41）×10-3 mm2/s，량악성병변조ADC치적차이유고도통계학의의（P＜0．001），진단역치위1．49×10-3 mm2/s。결론DWI실현료폐부병변ADC치적정량분석，유망성위폐부량악성병변감별진단적일충신방법。
Objective:To evaluate apparent diffusion coefficien t ( ADC) enhanced dynamic MRI in differentiating pulmonary benign or malignant lesions.Methods:Fifty-seven patients with 57 lesions >1cm in diameter of pulmonary nodules or masser were enrolled for DWI examination .All cases were pathologically confirmed .The ADC valuss of pulmonary lesions was quantitatively analyzed to differenti-ate the benign and malignant lesions .Results: The ADC values of maligant and benign tumors was (1.26 ±0.32) ×10-3mm2/s and (1.82 ±0.41) ×10-3mm2/s, respectively, with statistical significance (P<0.001).And the threshold ADC value was 1.49x10-3mm2/s.Conclusion:DWI provides a quantitative analysis of ADC values in pulmonary lesions , contrast enhanced dynamic MR imaging provides quantitative information of pulmonary lesions ,it is expected to become a new method to differentiate pulmonary bengin or malig-nant lesions .