中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
10期
31-32,33
,共3页
子宫平滑肌肿瘤%瘦素%肾上腺髓质素
子宮平滑肌腫瘤%瘦素%腎上腺髓質素
자궁평활기종류%수소%신상선수질소
Human uterine smooth muscle tumors%Leptin%ADM
目的:了解瘦素、肾上腺髓质素在子宫平滑肌肿瘤(UMST)中的表达及意义。方法:对30例良性子宫平滑肌瘤(UL)、30例富于性子宫平滑肌瘤(CL)及10例子宫平滑肌肉瘤(LMS)应用免疫组化法检测瘦素与肾上腺髓质素(ADM)的表达。结果:LMS组瘦素表达阳性率明显高于CL组和UL组(P<0.05),且CL组表达阳性率高于UL组(P<0.05);LMS组ADM表达阳性率明显高于CL组和UL组(P<0.05),且CL组表达阳性率高于UL组(P<0.05)。结论:瘦素和ADM的表达可能在UMST的发生、发展中起重要作用。
目的:瞭解瘦素、腎上腺髓質素在子宮平滑肌腫瘤(UMST)中的錶達及意義。方法:對30例良性子宮平滑肌瘤(UL)、30例富于性子宮平滑肌瘤(CL)及10例子宮平滑肌肉瘤(LMS)應用免疫組化法檢測瘦素與腎上腺髓質素(ADM)的錶達。結果:LMS組瘦素錶達暘性率明顯高于CL組和UL組(P<0.05),且CL組錶達暘性率高于UL組(P<0.05);LMS組ADM錶達暘性率明顯高于CL組和UL組(P<0.05),且CL組錶達暘性率高于UL組(P<0.05)。結論:瘦素和ADM的錶達可能在UMST的髮生、髮展中起重要作用。
목적:료해수소、신상선수질소재자궁평활기종류(UMST)중적표체급의의。방법:대30례량성자궁평활기류(UL)、30례부우성자궁평활기류(CL)급10례자궁평활기육류(LMS)응용면역조화법검측수소여신상선수질소(ADM)적표체。결과:LMS조수소표체양성솔명현고우CL조화UL조(P<0.05),차CL조표체양성솔고우UL조(P<0.05);LMS조ADM표체양성솔명현고우CL조화UL조(P<0.05),차CL조표체양성솔고우UL조(P<0.05)。결론:수소화ADM적표체가능재UMST적발생、발전중기중요작용。
Objective:To understand the expression and significance of Leptin and ADM in human uterine smooth muscle(USMTs). Method:Immunohistochemical technique was used to detect the expression of Leptin and ADM protein in 30 usual leiomyoma(UL),30 cellular leiomyoma(CL)and 10 leiomyosarcoma(LMS). Result:The positive Leptin protein expression rate of LMS group was apparently higher than the CL group and UL group(P<0.05),the positive Leptin protein expressin rate of the CL group was apparently higher than the UL group(P<0.05). The positive ADM protein expression rate of LMS was apparently higher than the CL group and UL group(P<0.05),the positive ADM protein expression rate of CL was apparently higher than the UL group(P<0.05). Conclusion:The expression of Leptin or ADM protein may play an important role in the occurrence and development of human uterine smooth muscie tumors.