中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
10期
10-12
,共3页
刘亚秋%林海波%陆必森%刘喜
劉亞鞦%林海波%陸必森%劉喜
류아추%림해파%륙필삼%류희
病毒性脑炎%心律失常%危险因素%Logistic回归分析
病毒性腦炎%心律失常%危險因素%Logistic迴歸分析
병독성뇌염%심률실상%위험인소%Logistic회귀분석
Viral encephalitis%Arrhythmias%Risk factors%Logistic regression analysis
目的:探讨病毒性脑炎并发心律失常的影响因素。方法:选取本院内科2010年1月-2012年12月共收治的90例临床资料完整的病毒性脑炎患儿作为研究对象,对患儿临床特征与心律失常的关系进行单因素和多因素回归分析,对各危险因素与心律失常发生情况之间的相关性使用spearman相关性检验进行分析。结果:90例中有42例病毒性脑炎患儿出现心律失常65例次,发生率46.7%(42/90),包括各类早搏、阵发性室上性心动过速、心房颤动、窦性心动过缓或过速、一度或二度房室传导阻滞(Ⅰ度或Ⅱ度AVB)等。单因素分析显示:频繁抽搐(抽搐反复发作时间超过3 d)、意识障碍、低年龄、心肌肌钙蛋白(cTnI)升高、低血钾与病毒性脑炎并发心律失常相关联(P<0.01);多因素Logistic回归分析显示:频繁抽搐、心肌肌钙蛋白Ⅰ升高与病毒性脑炎并发心律失常显著独立相关(P<0.05)。相关性分析结果显示:频繁抽搐与心律失常发生呈正相关(r=0.250,P=0.027),心肌肌钙蛋白I与心律失常发生呈正相关(r=0.382,P=0.001)。结论:频繁抽搐、心肌肌钙蛋白Ⅰ升高是病毒性脑炎发生心律失常的危险因素。
目的:探討病毒性腦炎併髮心律失常的影響因素。方法:選取本院內科2010年1月-2012年12月共收治的90例臨床資料完整的病毒性腦炎患兒作為研究對象,對患兒臨床特徵與心律失常的關繫進行單因素和多因素迴歸分析,對各危險因素與心律失常髮生情況之間的相關性使用spearman相關性檢驗進行分析。結果:90例中有42例病毒性腦炎患兒齣現心律失常65例次,髮生率46.7%(42/90),包括各類早搏、陣髮性室上性心動過速、心房顫動、竇性心動過緩或過速、一度或二度房室傳導阻滯(Ⅰ度或Ⅱ度AVB)等。單因素分析顯示:頻繁抽搐(抽搐反複髮作時間超過3 d)、意識障礙、低年齡、心肌肌鈣蛋白(cTnI)升高、低血鉀與病毒性腦炎併髮心律失常相關聯(P<0.01);多因素Logistic迴歸分析顯示:頻繁抽搐、心肌肌鈣蛋白Ⅰ升高與病毒性腦炎併髮心律失常顯著獨立相關(P<0.05)。相關性分析結果顯示:頻繁抽搐與心律失常髮生呈正相關(r=0.250,P=0.027),心肌肌鈣蛋白I與心律失常髮生呈正相關(r=0.382,P=0.001)。結論:頻繁抽搐、心肌肌鈣蛋白Ⅰ升高是病毒性腦炎髮生心律失常的危險因素。
목적:탐토병독성뇌염병발심률실상적영향인소。방법:선취본원내과2010년1월-2012년12월공수치적90례림상자료완정적병독성뇌염환인작위연구대상,대환인림상특정여심률실상적관계진행단인소화다인소회귀분석,대각위험인소여심률실상발생정황지간적상관성사용spearman상관성검험진행분석。결과:90례중유42례병독성뇌염환인출현심률실상65례차,발생솔46.7%(42/90),포괄각류조박、진발성실상성심동과속、심방전동、두성심동과완혹과속、일도혹이도방실전도조체(Ⅰ도혹Ⅱ도AVB)등。단인소분석현시:빈번추휵(추휵반복발작시간초과3 d)、의식장애、저년령、심기기개단백(cTnI)승고、저혈갑여병독성뇌염병발심률실상상관련(P<0.01);다인소Logistic회귀분석현시:빈번추휵、심기기개단백Ⅰ승고여병독성뇌염병발심률실상현저독립상관(P<0.05)。상관성분석결과현시:빈번추휵여심률실상발생정정상관(r=0.250,P=0.027),심기기개단백I여심률실상발생정정상관(r=0.382,P=0.001)。결론:빈번추휵、심기기개단백Ⅰ승고시병독성뇌염발생심률실상적위험인소。
Objective:To explore the risk factors of viral encephalitis complicated with arrhythmia.Method:90 children with viral encephalitis in our hospital from January 2010 to December 2012 were selected as research objects. All clinical data were reviewed,linear relationship analysis with spearman correlation coefficients was used to study the correlations of some factors.Result:42 arrhythmias occurred in 90 patients(46.7%),arrhythmias consisted of premature complexes beat,supraventricular tachycardia,sinus tachycardia,sinus bradycardia,ⅠandⅡAVB et al.Single factor analysis showed that convulsions,consciousness obstruct,lower age,increase of cTnI,hypokalemia were risk factors of arrhythmias in children with viral encephalitis(P<0.01).Multivariate logistic regression analysis showed that convulsions and increase of cTnI were important risk factors to viral encephalitis with arrhythmias(P<0.05).Firstly in linear relationship analysis,arrhythmias was related to time of convulsions,and the correlation coefficient was 0.250(P=0.027),secondly increase of cTnI was also related to arrhythmias,and the correlation coefficient was 0.382(P=0.001).Conclusion:Convulsions and increase of cTnI are important risk factors to viral encephalitis with arrhythmias.