中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
z1期
17-18
,共2页
西地兰%硫酸镁%风湿性心脏病%急性心力衰竭%治疗
西地蘭%硫痠鎂%風濕性心髒病%急性心力衰竭%治療
서지란%류산미%풍습성심장병%급성심력쇠갈%치료
Cedilanid%Magnesium sulfate%Rheumatic heart disease%Chronic heart failure%Treatment
目的 研究西地兰联合镁离子极化液治疗风湿性心脏病心衰的临床疗效及安全性.方法 选用风湿性心脏病心衰患者119例,随机分为实验组60例和参照组59例,对参照组采用0.4 mg西地兰加入20ml的10％的葡萄糖溶液实施静脉缓慢注射,10 min内完成注射,1次/d,持续用药7d.对实验组采用25％的镁离子极化液(硫酸镁)20 ml+ 0.4 mg西地兰参加入20ml的10％的葡萄糖溶液进行静脉缓慢注射,10min内完成注射,1次/d,持续用药7d.治疗过程中,对两组患者实施抗感染、吸氧、纠正酸碱失衡等常规治疗；并认真观察患者血压、心率和心律的变化情况.结果 实验组的60例患者中,55例患者的心功能取得明显改善,总有效率为91.67％；在参照组59例患者中,42例患者的心功能出现明显的提升,总有效率为71.19％.实验组患者心功能改善情况显著优于参照组,两组患者心功能改善的总有效率差距具有统计学意义(P＜0.05).结论 对于风湿性心脏病急性心力衰竭疾病的治疗,采用西地兰和镁离子极化液联合治疗的办法,能够显著改善患者心功能,增强治疗作用,值得推广应用.
目的 研究西地蘭聯閤鎂離子極化液治療風濕性心髒病心衰的臨床療效及安全性.方法 選用風濕性心髒病心衰患者119例,隨機分為實驗組60例和參照組59例,對參照組採用0.4 mg西地蘭加入20ml的10％的葡萄糖溶液實施靜脈緩慢註射,10 min內完成註射,1次/d,持續用藥7d.對實驗組採用25％的鎂離子極化液(硫痠鎂)20 ml+ 0.4 mg西地蘭參加入20ml的10％的葡萄糖溶液進行靜脈緩慢註射,10min內完成註射,1次/d,持續用藥7d.治療過程中,對兩組患者實施抗感染、吸氧、糾正痠堿失衡等常規治療；併認真觀察患者血壓、心率和心律的變化情況.結果 實驗組的60例患者中,55例患者的心功能取得明顯改善,總有效率為91.67％；在參照組59例患者中,42例患者的心功能齣現明顯的提升,總有效率為71.19％.實驗組患者心功能改善情況顯著優于參照組,兩組患者心功能改善的總有效率差距具有統計學意義(P＜0.05).結論 對于風濕性心髒病急性心力衰竭疾病的治療,採用西地蘭和鎂離子極化液聯閤治療的辦法,能夠顯著改善患者心功能,增彊治療作用,值得推廣應用.
목적 연구서지란연합미리자겁화액치료풍습성심장병심쇠적림상료효급안전성.방법 선용풍습성심장병심쇠환자119례,수궤분위실험조60례화삼조조59례,대삼조조채용0.4 mg서지란가입20ml적10％적포도당용액실시정맥완만주사,10 min내완성주사,1차/d,지속용약7d.대실험조채용25％적미리자겁화액(류산미)20 ml+ 0.4 mg서지란삼가입20ml적10％적포도당용액진행정맥완만주사,10min내완성주사,1차/d,지속용약7d.치료과정중,대량조환자실시항감염、흡양、규정산감실형등상규치료；병인진관찰환자혈압、심솔화심률적변화정황.결과 실험조적60례환자중,55례환자적심공능취득명현개선,총유효솔위91.67％；재삼조조59례환자중,42례환자적심공능출현명현적제승,총유효솔위71.19％.실험조환자심공능개선정황현저우우삼조조,량조환자심공능개선적총유효솔차거구유통계학의의(P＜0.05).결론 대우풍습성심장병급성심력쇠갈질병적치료,채용서지란화미리자겁화액연합치료적판법,능구현저개선환자심공능,증강치료작용,치득추엄응용.
Objective To study the clinical efficacy and safety of cedilanid and magnesium polarization liquid in treatment of rheumatic heart disease and heart failure.Methods Select 119 rheumatic heart disease patients with heart failure treatment during my hospital in 2010 6 to 2012 March,randomly divided them into experimental group 60 cases and control group 59 cases,glucose solution to the reference group using 0.4 mg cedilanid join 20 ml 10％ implementation slow intravenous injection,10 min after injection,1/d 7 d,continued drug use.The experimental group used magnesium polarization liquid 25％(magnesium sulfate) glucose solution 20 ml + 0.4 mg cedilanid joined in the 10％ 20 ml was intravenously administered,the completion of the injection 10 min,1/d,continuous administration of 7 d.In the course of treatment,on the implementation of two groups of patients anti-infection,oxygen inhalation,correction of acid-base balance and other conventional treatment; changes and careful observation of blood pressure,heart rate and cardiac patients.Results 60 patients in the experimental group,the cardiac function of 55 patients has significantly improved,the total effective rate was 91.67％ ; in the control group of 59 patients,cardiac function of 42 patients were improved,the total effective rate was 71.19％.The experimental group improved cardiac function was significantly better than the control group,two patients with cardiac function improvement of total efficiency gap with statistical significance (P ＜ 0.05).Conclusion For the treatment of rheumatic heart disease and chronic heart failure disease,with cedilanid and magnesium polarization liquid treatment method,can significantly improve cardiac function,enhance the treatment effect,it is worthy of popularization and application.
