CAJ | 학술논문

以2-乙酰基庚酸乙酯为底物模型,考察了酵母细胞在水相体系中催化其不对称还原的反应特性。利用正交实验初步优化反应条件,并在此基础上,兼顾反应的时-空产率,系统地研究了初始底物浓度、酵母细胞浓度、反应温度对反应转化率的影响。产品表征结果为目标产物,经测定具有光学活性。
이2-을선기경산을지위저물모형,고찰료효모세포재수상체계중최화기불대칭환원적반응특성。이용정교실험초보우화반응조건,병재차기출상,겸고반응적시-공산솔,계통지연구료초시저물농도、효모세포농도、반응온도대반응전화솔적영향。산품표정결과위목표산물,경측정구유광학활성。
The asymmetric reduction by yeast cells in aqueous phase was investigated when 2- acetyl ethyl heptanoate was chosen as the substrate. The asymmetric reduction of 2-acetyl ethyl heptanoate by yeast cells was investigated respectively in this work. The effects of reaction conditions, such as initial substrate concentration, cell concentration, reaction pH were investigated by orthogonal experiment. Product characterization results for the target product with opcical activity.