中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
CHINESE PEDIATRIC EMERGENCY MEDICINE
2014年
6期
362-365
,共4页
脑干听觉诱发电位%重症手足口病%神经系统损害%早期诊断
腦榦聽覺誘髮電位%重癥手足口病%神經繫統損害%早期診斷
뇌간은각유발전위%중증수족구병%신경계통손해%조기진단
Brainstem auditory evoked potential%Severe hand,foot and mouth disease%Nervous system damage%Early diagnosis
目的 探讨脑干听觉诱发电位(brainstem auditory evoked potential,BAEP)对手足口病重症病例神经系统损害的早期诊断价值.方法 本研究通过对297例手足口病患儿进行BAEP检测,之后按照严重程度分级及年龄进行分组比较,手足口病普通病例、年龄＜3岁为A组(n=80),重症病例重型、年龄＜3岁为B组(n=94),普通病例、年龄≥3岁为C组(n=38),重症病例重型、年龄≥3岁为D组(n=85).回顾性分析各组脑电图(electroencephalogram,EEG)、头部MRI的检测结果,并与BAEP结果进行比较.结果 (1)B组BAEP异常率(18/94,19.15％)高于A组(3/80,3.75％),D组BAEP异常率(13/85,15.29％)高于C组(1/38,2.63％),差异有统计学意义(P＜0.05).(2)B组EEG异常率偏低(2/94,2.13％),A组无一例EEG异常.(3)D组EEG异常率(49/85,57.65％)高于C组(6/38,15.79％) (P ＜0.05),且高于D组BAEP异常率.(4)B组MRI异常率(9/94,9.57％)高于A组(1/80,1.25％)(P＜0.05),D组MRI异常率(9/85,10.59％)高于C组(0).(5)全部手足口病重症病例重型患儿的BAEP异常率(31/179,17.32％)高于MRI异常率(18/179,10.06％) (P＜0.05).结论 BAEP检测可为手足口病重症病例神经系统损害的早期诊断提供客观依据.
目的 探討腦榦聽覺誘髮電位(brainstem auditory evoked potential,BAEP)對手足口病重癥病例神經繫統損害的早期診斷價值.方法 本研究通過對297例手足口病患兒進行BAEP檢測,之後按照嚴重程度分級及年齡進行分組比較,手足口病普通病例、年齡＜3歲為A組(n=80),重癥病例重型、年齡＜3歲為B組(n=94),普通病例、年齡≥3歲為C組(n=38),重癥病例重型、年齡≥3歲為D組(n=85).迴顧性分析各組腦電圖(electroencephalogram,EEG)、頭部MRI的檢測結果,併與BAEP結果進行比較.結果 (1)B組BAEP異常率(18/94,19.15％)高于A組(3/80,3.75％),D組BAEP異常率(13/85,15.29％)高于C組(1/38,2.63％),差異有統計學意義(P＜0.05).(2)B組EEG異常率偏低(2/94,2.13％),A組無一例EEG異常.(3)D組EEG異常率(49/85,57.65％)高于C組(6/38,15.79％) (P ＜0.05),且高于D組BAEP異常率.(4)B組MRI異常率(9/94,9.57％)高于A組(1/80,1.25％)(P＜0.05),D組MRI異常率(9/85,10.59％)高于C組(0).(5)全部手足口病重癥病例重型患兒的BAEP異常率(31/179,17.32％)高于MRI異常率(18/179,10.06％) (P＜0.05).結論 BAEP檢測可為手足口病重癥病例神經繫統損害的早期診斷提供客觀依據.
목적 탐토뇌간은각유발전위(brainstem auditory evoked potential,BAEP)대수족구병중증병례신경계통손해적조기진단개치.방법 본연구통과대297례수족구병환인진행BAEP검측,지후안조엄중정도분급급년령진행분조비교,수족구병보통병례、년령＜3세위A조(n=80),중증병례중형、년령＜3세위B조(n=94),보통병례、년령≥3세위C조(n=38),중증병례중형、년령≥3세위D조(n=85).회고성분석각조뇌전도(electroencephalogram,EEG)、두부MRI적검측결과,병여BAEP결과진행비교.결과 (1)B조BAEP이상솔(18/94,19.15％)고우A조(3/80,3.75％),D조BAEP이상솔(13/85,15.29％)고우C조(1/38,2.63％),차이유통계학의의(P＜0.05).(2)B조EEG이상솔편저(2/94,2.13％),A조무일례EEG이상.(3)D조EEG이상솔(49/85,57.65％)고우C조(6/38,15.79％) (P ＜0.05),차고우D조BAEP이상솔.(4)B조MRI이상솔(9/94,9.57％)고우A조(1/80,1.25％)(P＜0.05),D조MRI이상솔(9/85,10.59％)고우C조(0).(5)전부수족구병중증병례중형환인적BAEP이상솔(31/179,17.32％)고우MRI이상솔(18/179,10.06％) (P＜0.05).결론 BAEP검측가위수족구병중증병례신경계통손해적조기진단제공객관의거.
Objective To investigate the value of brainstem auditory evoked potential (BAEP) in early diagnosis of severe hand,foot and mouth disease (HFMD) with the nervous system damage.Methods BAEP was performed in 297 cases with HFMD.The patients were divided into 4 groups by the HFMD clinical classification and their ages.Group A included the general cases who were younger than three years (n =80).Group B included the severe cases who were younger than three years(n =94).Group C included the general cases who were three years or older(n =38).Group D included the severe cases who were three years or older(n =85).The electroencephalogram (EEG) and MRI results of patients in the groups were retrospectively studied and the results were compared with that of BAEP.Results (1) The BAEP abnormal rate of group B (18/94,19.15％)was higher than that of group A (3/80,3.75％),and the BAEP abnormal rate of group D (13/85,15.29％) was higher than that of group C (1/38,2.63％) (P ＜ 0.05).(2) The EEG abnormal rate in group B was low(2/94,2.13％) and there was no case with abnormal EEG in group A.(3) The EEG abnormal rate of group D (49/85,57.65％) was higher than that of group C (6/38,15.79％) (P ＜0.05),and higher than the BAEP abnormal rate of group D.(4) The MRI abnormal rate of group B (9/94,9.57％) was higher than that of group A (1/80,1.25％) (P ＜ 0.05),and the MRI abnormal rate of group D (9/85,10.59％)was higher than that of group C (0).(5) The BAEP abnormal rate of the children with severe HFMD (31/179,17.32％) was higher than the MRI abnormal rate (18/179,10.06％) (P ＜0.05).Conclusion BAEP has clinical significance for early diagnosis of severe HFMD with nervous system damage,and can provide objective basis for the diagnosis.
