CAJ | 학술논문

目的眼眶内容剜除术是一种破坏性手术,主要用于眼眶恶性肿瘤的治疗.文中收集了189例眶内容剜除术患者的临床资料进行分析.方法回顾性分析1999年11月至2010年8月在武警总医院眼眶病研究所进行眶内容物剜除术的189例患者资料.用Kaplan-Meier生存分析对眶内容剜除术后患者的生存率及不同病理类型患者的生存率进行评估.结果 178例患者采用全眶内容剜除术,6例实施前部眶内容剜除术,5例实施后部眶内容剜除术.对189例眶内容剜除术患者的一般临床特征、临床症状、肿瘤原发部位及术后病理分型进行了分析.此外对13例术后出现并发症的原因进行了分析.结论研究表明最常见行眶内容剜除术的病理类型为腺样囊性癌、其次是恶性黑色素瘤、位于第三位的是视网膜母细胞瘤.对浸润性的非恶性肿瘤的分析表明,局部切除术后复发是导致最终行眶内容剜除术的重要原因,提示对良性肿瘤行初次局部切除手术治疗的重要性.尽管眶内容手术属于姑息性、极端性的手术方式,但并不意味着可以忽视对眶内容剜除术患者的复查随访,而出现术后并发症的患者经过积极的对症处理,也能得到有效地控制或完全的治愈.
목적 안광내용완제술시일충파배성수술,주요용우안광악성종류적치료.문중수집료189례광내용완제술환자적림상자료진행분석.방법 회고성분석1999년11월지2010년8월재무경총의원안광병연구소진행광내용물완제술적189례환자자료.용Kaplan-Meier생존분석대광내용완제술후환자적생존솔급불동병리류형환자적생존솔진행평고.결과 178례환자채용전광내용완제술,6례실시전부광내용완제술,5례실시후부광내용완제술.대189례광내용완제술환자적일반림상특정、림상증상、종류원발부위급술후병리분형진행료분석.차외대13례술후출현병발증적원인진행료분석.결론 연구표명최상견행광내용완제술적병리류형위선양낭성암、기차시악성흑색소류、위우제삼위적시시망막모세포류.대침윤성적비악성종류적분석표명,국부절제술후복발시도치최종행광내용완제술적중요원인,제시대량성종류행초차국부절제수술치료적중요성.진관광내용수술속우고식성、겁단성적수술방식,단병불의미착가이홀시대광내용완제술환자적복사수방,이출현술후병발증적환자경과적겁적대증처리,야능득도유효지공제혹완전적치유.
Objective Orbital exenteration is a destructive procedure reserved for the treatment of locally invasive malignancy or potentially life threatening orbital neoplasms.The authors report their experience and analyse of 189 cases of orbital exenteration performed over an 11 year period,and this is a large-scale clinical research.Methods Records were reviewed retrospectively of all patients who had undergone exenteration of the orbit from November 1999 to April 2010 inclusive,at Armed Police General Hospital.Kaplan-Meier analysis was used to estimate survival following exenteration and pathologicaldiagnosis.Results 178 cases were undergone full orbital exenteration,and 11 cases with partial orbitalexenteration.Records of patient's clinical symptoms,original site and pathology results were reviewed and analyzed.In 13 cases,causes of post-operation complications had been analyzed.ConclusionIn this study it was found that adenoid cystic carcinoma was the most common pathological diagnosis leading to exenteration,followed by malignant melanoma,and retinoblastorna.In the whole nonmalignant group,local recurrence following the original local resection was the key factor that leading to the orbital exenteration,which remindedthe importance of the original excision.Although the orbital exenteration was palliative and destructive,allcomplications had been well resolved pointing us that timely symptomatic treatments and regular follow-up should be well done.