CAJ | 학술논문

代谢组学是研究生物体被扰动后内源性代谢物变化规律的系统科学,其在慢性气道炎症性疾病如支气管哮喘、慢性阻塞性肺疾病中的应用研究成为热点,有望通过对慢性气道炎症性疾病患者的代谢轮廓分析,寻找到有意义的生物标记物并探索疾病的发病机制.本文就研究现状作一综述,并展望其发展前景.
대사조학시연구생물체피우동후내원성대사물변화규률적계통과학,기재만성기도염증성질병여지기관효천、만성조새성폐질병중적응용연구성위열점,유망통과대만성기도염증성질병환자적대사륜곽분석,심조도유의의적생물표기물병탐색질병적발병궤제.본문취연구현상작일종술,병전망기발전전경.
Metabolomics is a systematic science that mainly studies the dynamic changes of endogenous metabolites after a biological system is stimulated or disturbed.Its application in chronic respiratory inflammatory diseases like chronic obstructive pulmonary disease and asthma has increasingly been explored,with an attempt to find valuable biomarkers and explore the underlying pathogenesis of chronic respiratory inflammatory diseases by profiling the metabolism in these patients.This article summarizes recent advances in this topic and outlines prospects for future developments.