中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
2期
175-178
,共4页
贾洪强%刘敏%刘玉军%徐深
賈洪彊%劉敏%劉玉軍%徐深
가홍강%류민%류옥군%서심
重度非增生性糖尿病视网膜病变%早期增生性糖尿病视网膜病变%全视网膜光凝%视网膜神经纤维层%光学相干断层扫描
重度非增生性糖尿病視網膜病變%早期增生性糖尿病視網膜病變%全視網膜光凝%視網膜神經纖維層%光學相榦斷層掃描
중도비증생성당뇨병시망막병변%조기증생성당뇨병시망막병변%전시망막광응%시망막신경섬유층%광학상간단층소묘
Severe non-proliferative diabetic retinopathy%Early proliferative diabetic retinopathy%Panretinal photocoagulation%Retinal nerve fiber layer%Optical coherence tomography
目的 探讨并分析糖尿病视网膜病变(diabetic retinopathy,DR),重度非增生性DR(non-proliferative diabetic retinopathy,NPDR)和早期增生性DR (proliferative diabetic retinopathy,PDR)患者全视网膜光凝术(panretinal photocoagulation,PRP),术前及术后6个月视盘周围视网膜神经纤维层(Retinal Nerve Fiber Layer,RNFL)厚度的变化.方法 临床病例对照研究.对2010年5月至2011年5月在沧州眼科医院应用光学相干断层扫描技术(optical coherence tomography,OCT)测量已确诊的共53例(93只眼),其中重度NPDR组26例和早期PDR组27例,测其PRP前后视盘周围RN-FL的厚度,采用单因素方差分析对PRP前后视盘周围各象限及全周平均RNFL厚度进行两两比较分析.结果 重度NPDR和早期PDR组PRP术后6个月上、下象限及视盘周围平均RNFL厚度较薄,与术前比较差异有统计学意义.术后6个月上方、下方及鼻侧象限早期PDR组较重度NPDR组变薄,两者比较差异有统计学意义.结论 激光光凝前应充分考虑其对视网膜RNFL的影响,PRP后6个月视盘周围RNFL厚度变薄,尤以上、下象限及全周平均RNFL较明显.
目的 探討併分析糖尿病視網膜病變(diabetic retinopathy,DR),重度非增生性DR(non-proliferative diabetic retinopathy,NPDR)和早期增生性DR (proliferative diabetic retinopathy,PDR)患者全視網膜光凝術(panretinal photocoagulation,PRP),術前及術後6箇月視盤週圍視網膜神經纖維層(Retinal Nerve Fiber Layer,RNFL)厚度的變化.方法 臨床病例對照研究.對2010年5月至2011年5月在滄州眼科醫院應用光學相榦斷層掃描技術(optical coherence tomography,OCT)測量已確診的共53例(93隻眼),其中重度NPDR組26例和早期PDR組27例,測其PRP前後視盤週圍RN-FL的厚度,採用單因素方差分析對PRP前後視盤週圍各象限及全週平均RNFL厚度進行兩兩比較分析.結果 重度NPDR和早期PDR組PRP術後6箇月上、下象限及視盤週圍平均RNFL厚度較薄,與術前比較差異有統計學意義.術後6箇月上方、下方及鼻側象限早期PDR組較重度NPDR組變薄,兩者比較差異有統計學意義.結論 激光光凝前應充分攷慮其對視網膜RNFL的影響,PRP後6箇月視盤週圍RNFL厚度變薄,尤以上、下象限及全週平均RNFL較明顯.
목적 탐토병분석당뇨병시망막병변(diabetic retinopathy,DR),중도비증생성DR(non-proliferative diabetic retinopathy,NPDR)화조기증생성DR (proliferative diabetic retinopathy,PDR)환자전시망막광응술(panretinal photocoagulation,PRP),술전급술후6개월시반주위시망막신경섬유층(Retinal Nerve Fiber Layer,RNFL)후도적변화.방법 림상병례대조연구.대2010년5월지2011년5월재창주안과의원응용광학상간단층소묘기술(optical coherence tomography,OCT)측량이학진적공53례(93지안),기중중도NPDR조26례화조기PDR조27례,측기PRP전후시반주위RN-FL적후도,채용단인소방차분석대PRP전후시반주위각상한급전주평균RNFL후도진행량량비교분석.결과 중도NPDR화조기PDR조PRP술후6개월상、하상한급시반주위평균RNFL후도교박,여술전비교차이유통계학의의.술후6개월상방、하방급비측상한조기PDR조교중도NPDR조변박,량자비교차이유통계학의의.결론 격광광응전응충분고필기대시망막RNFL적영향,PRP후6개월시반주위RNFL후도변박,우이상、하상한급전주평균RNFL교명현.
Objective To investigate and analyze retinal nerve fiber layer (RNFL) thickness changes in patients of diabetic retinopathy (DR) with severe non-proliferative DR (NPDR) and early proliferative DR (PDR) with panretinal photocoagulation (PRP) before surgery and 6 months after surgery peripapillary.Methods Optical coherence tomography (OCT) scanning technology was used to measure the RNFL thickness around disc of the 53 patients (93 eyes) with severe NPDR and early PDR with PRP front and rear,one-way ANOVA was used for statistics analysis the average RNFL thickness of each quadrant,front,rear and whole around the disc of PRP,difference was statistically significant (P ＜0.05).Results RNFL thickness on the lower quadrant and peripapillary was thin on severe NPDR and early PDR group 6 months after PRP,the difference was statistically significant compared with the preoperative.The RNFL thinning on top,bottom,and nasal quadrant were heavier on early PDR group than NPDR group 6 months after surgery,the difference was statistically significant.Conclusions Laser photocoagulation should be given full consideration to the RNFL thickness on the peripapillary,these become thinner 6 months after the PRP,especially over the lower quadrant and whole average RNFL.
