CAJ | 학술논문

目的应用自制-80℃冻干猪二道皮(类似仿猪真皮)覆盖Ⅱ度烧伤创面,改进传统的换药方法并评价其效果.方法取小型健康白色家猪的新鲜皮,经常规清洁剃毛,以电动取皮机去脂,制成去表皮刃厚猪二道皮,经处理后放入-80℃冰箱冻存备用.临床分为两组:A组为观察组共42例,以猪二道皮覆盖创面,B组为对照组共76例,以10%磺胺嘧啶银霜油纱布传统方法交敷创面.结果浅Ⅱ度创面愈合时间,A组平均(10.67±2.08)天,B组(13.1±1.73)天(P<0.01);深Ⅱ度创面愈合时间,A组平均(20.8±2.03)天,B组(23.20±2.60)天(P<0.01).结论与传统的换药方法相比,以猪二道皮覆盖烧伤创面,能促进上皮细胞生长,减轻疼痛,缩短愈合时间,减少疤痕和畸形的产生.
목적 응용자제-80℃동간저이도피(유사방저진피)복개Ⅱ도소상창면,개진전통적환약방법병평개기효과.방법 취소형건강백색가저적신선피,경상규청길체모,이전동취피궤거지,제성거표피인후저이도피,경처리후방입-80℃빙상동존비용.림상분위량조:A조위관찰조공42례,이저이도피복개창면,B조위대조조공76례,이10%광알밀정은상유사포전통방법교부창면.결과 천Ⅱ도창면유합시간,A조평균(10.67±2.08)천,B조(13.1±1.73)천(P<0.01);심Ⅱ도창면유합시간,A조평균(20.8±2.03)천,B조(23.20±2.60)천(P<0.01).결론 여전통적환약방법상비,이저이도피복개소상창면,능촉진상피세포생장,감경동통,축단유합시간,감소파흔화기형적산생.
Objective　To improve the dressing methods of second degree burn wounds and evaluate therapeutic effectiveness of porcine dermis freezed drying in -80℃. Methods　Split thickness skin including cuticular layer removed from the full-thickness skins of small piglets after cleaning, shaving and degreasing, then preserve uncalled porcine dermis in below zero 80 centi-degree refrigerator. The second burn wounds of 118 patients were radomly devided into two groups: experiments group dressed with porcine dermis in 42 patients and control group dressed with traditional method of vestine bandage containing 10 percent silver sulfadiazine frost. Results　The superficial second-degree burn wounds in experiment group were cured in 10.67±2.08 days(P<0.01),less than control group(13.1±1.73 days).Similarly, deep second degree burn wounds in experiment group were cured in 20.8±2.03 days,wheres control group 23.20±2.60 days(P<0.01). Conclusions　Comparing with tradional wound dressing methods, the method of covering wound with improvable dermis dressing from removal porcine full-thickness skins might stimulate growth of endothelial cells of wounds, with less pain，shorter healing period and less scar.