CAJ | 학술논문

　　目的了解当前小儿院内获得性肺炎（HAP）病毒病原学的状况。方法收集251例HAP的患儿资料，对其中做痰液病毒分离，获得合胞病毒（RSV）、流感病毒、副流感病毒病原学检测阳性结果的病例进行分析。结果251例HAP患儿中141例做了痰液病毒检测，其中阳性67例，病毒检出率为47.52%（67/141），其中以RSV肺炎最为多见。67例病毒性HAP均以喘息为主要临床表现，多数不发热或低热，少部分可以表现为高热，血常规、CRP基本正常。67例中22例有明确的诱因，其中以使用激素最为多见。67例患儿均治疗有效。结论251例住院患儿中HAP病毒检出以呼吸道合胞病毒为主，预后均良好。
　　목적료해당전소인원내획득성폐염（HAP）병독병원학적상황。방법수집251례HAP적환인자료，대기중주담액병독분리，획득합포병독（RSV）、류감병독、부류감병독병원학검측양성결과적병례진행분석。결과251례HAP환인중141례주료담액병독검측，기중양성67례，병독검출솔위47.52%（67/141），기중이RSV폐염최위다견。67례병독성HAP균이천식위주요림상표현，다수불발열혹저열，소부분가이표현위고열，혈상규、CRP기본정상。67례중22례유명학적유인，기중이사용격소최위다견。67례환인균치료유효。결론251례주원환인중HAP병독검출이호흡도합포병독위주，예후균량호。
Objective To identify viral pathogens from Children with hospital- acquired pneumonia (HAP). Methods The clinical data of 251 child patients with HAP admitted to hospital from January 2009 to December 2011, among whom 141 cases had sputum viral examination, were retrospectively analyzed. Results Among 141 patients, viruses were detected in sputum samples in 67 cases with a detection rate of 47.52%(67/141). Respiratory syncytial virus (RSV) was the most prevalent virus and accounted for 83.58% of the total (57/67). Asthma was the main symptom in al patients. High fever developed in a few cases, however, most patients had no fever or a low fever. The blood test and CRP presented normal levels. Among 67 cases, 22 had definite disease causes, which was related to hormone use. The treatments were effective in al patients. Conclusion Respiratory syncytial virus is the predominant etiology for child hospital- acquired pneumonia in Children's Hospital affiliated to Wenzhou Medical Col ege from 2009 to 2011.