CAJ | 학술논문

　　目的对肠道病毒EV71感染重症手足口病患儿进行随访分析，了解预后情况。方法对2011年3～12月新乡市中心医院收治的33例确诊为肠道病毒EV71感染的重症手足口病患儿出院后3个月进行跟踪随访，观察预后情况。结果肠道病毒EV71感染重症手足口病33例患儿入院时均有不同程度的嗜睡、精神状态的改变（萎靡和烦躁）以及四肢抖动、惊跳等中枢神经系统表现，经治疗后有2例遗留有不同程度的后遗症，余均预后良好。结论肠道病毒EV71更易致中枢神经系统损害及AFP且具有发病年龄小，病情凶险，病死率高的特点，及早发现、及时干预治疗可减轻其预后。
　　목적대장도병독EV71감염중증수족구병환인진행수방분석，료해예후정황。방법대2011년3～12월신향시중심의원수치적33례학진위장도병독EV71감염적중증수족구병환인출원후3개월진행근종수방，관찰예후정황。결과장도병독EV71감염중증수족구병33례환인입원시균유불동정도적기수、정신상태적개변（위미화번조）이급사지두동、량도등중추신경계통표현，경치료후유2례유류유불동정도적후유증，여균예후량호。결론장도병독EV71경역치중추신경계통손해급AFP차구유발병년령소，병정흉험，병사솔고적특점，급조발현、급시간예치료가감경기예후。
Objective To follow up the children with Enterovirus 71 (EV71) infected severe hand-foot-mouth disease in order to understand the prognosis. Methods Thirty-three children diagnosed with EV71 infected severe hand-foot-mouth disease treated in the Xinxiang Central Hospital from March to December 2011 were followed up 3 months after discharge and the prognosis was observed. Results On admission to the hospital, all the 33 children with EV71 infected severe hand-foot-mouth disease had varying degrees of lethargy, mental status changes (malaise and irritability) and central nervous system manifestations such as limb shake and startle. After the treatment, 2 children were left with different degrees of sequelae and the rest had a good prognosis. Conclusion EV 71 is more prone to causing central nervous system damage and AFP and has the characteristics such as low age of disease onset, dangerous conditions and high mortality. Early detection and timely intervention can improve the prognosis.