CAJ | 학술논문

目的探索激光治疗早产儿视网膜病变(ROP)疗效及预后的影响因素.方法回顾性分析2011年3月至2012年7月在吉林大学第一医院新生儿科收治的20例行810 nm激光治疗ROP早产儿的相关临床数据,并进行统计学分析.结果共有20例患儿(40只眼)行激光治疗.Ⅰ区病变18只眼,Ⅱ区病变22只眼.平均出生体重1 433.25 g,平均胎龄30.05周,治疗时矫正胎龄31～43周,平均矫正胎龄37.25周.一次激光治愈38只眼,治愈率为95％ (38/40).病变部位与统计的各临床因素(孕次、产次、胎龄、出生体重、矫正胎龄、激光治疗年龄、新生儿低血糖、坏死性小肠结肠炎、肺炎、败血症、新生儿窒息等11个临床因素)差异无统计学意义(P＞0.05).结论 810 nm激光光凝治疗ROP是安全有效的,治疗效果与患儿临床因素关系不大,与治疗时机的选择有关.
목적 탐색격광치료조산인시망막병변(ROP)료효급예후적영향인소.방법 회고성분석2011년3월지2012년7월재길림대학제일의원신생인과수치적20례행810 nm격광치료ROP조산인적상관림상수거,병진행통계학분석.결과 공유20례환인(40지안)행격광치료.Ⅰ구병변18지안,Ⅱ구병변22지안.평균출생체중1 433.25 g,평균태령30.05주,치료시교정태령31～43주,평균교정태령37.25주.일차격광치유38지안,치유솔위95％ (38/40).병변부위여통계적각림상인소(잉차、산차、태령、출생체중、교정태령、격광치료년령、신생인저혈당、배사성소장결장염、폐염、패혈증、신생인질식등11개림상인소)차이무통계학의의(P＞0.05).결론 810 nm격광광응치료ROP시안전유효적,치료효과여환인림상인소관계불대,여치료시궤적선택유관.
Objective To explore the treatment outcome for retinopathy of prematurity by 810 nm diode laser photocoagulation and the prognostic factors.Methods The clinic data from 20 ROP preterm infants treated in the first affiliated hospital of Jilin University from March 2011 to July 2012 were retrospectively analyzed.Results A total of 20 patients(40 eyes)underwent laser therapy.There were 18 eyes with zone 1,22 eyes with zone 2.The mean birth weight and the gestational age was 1433.25g and 30.05 weeks,respectively.The corrected gestational age at the time of operation was 31 weeks to 43 weeks,the mean corrected gestational age was 37.25 weeks.There were no significant diffreneces in gravidity,parity,gestational age,birth weight,corrected gestational age,age at laser,neonatal hypoglycemia between zone 1 and zone 2 (P ＞0.05).Conclusion 810 nm diode laser retinal photocoagulation is a safe and effective procedure for treatment of ROP.The treatment outcome is associated with the diode laser opportunity rather than such certain clinical risk factors.