CAJ | 학술논문

　　目的探讨超声造影在结节性甲状腺肿背景下良、恶性结节鉴别诊断中的应用价值。方法对结节性甲状腺肿疾病中的105个可疑结节均进行超声造影检查，分析其增强特点，所有病灶均经手术病理结果证实。结果恶性结节主要呈低增强（44.8%，30/67），良性结节主要呈等增强（39.5%，15/38），差异有统计学意义（P＜0.05）；良、恶性结节均以不均匀增强表现为主（60.5%、68.7%），差异无统计学意义（P＞0.05）。恶性结节主要呈慢进同出（62.7%，42/67），良性结节主要呈同进同出（50%，19/38），差异具有统计学意义（P＜0.01）。结论超声造影对鉴别结节性甲状腺肿背景下良、恶性结节有一定的诊断价值。
　　목적탐토초성조영재결절성갑상선종배경하량、악성결절감별진단중적응용개치。방법대결절성갑상선종질병중적105개가의결절균진행초성조영검사，분석기증강특점，소유병조균경수술병리결과증실。결과악성결절주요정저증강（44.8%，30/67），량성결절주요정등증강（39.5%，15/38），차이유통계학의의（P＜0.05）；량、악성결절균이불균균증강표현위주（60.5%、68.7%），차이무통계학의의（P＞0.05）。악성결절주요정만진동출（62.7%，42/67），량성결절주요정동진동출（50%，19/38），차이구유통계학의의（P＜0.01）。결론초성조영대감별결절성갑상선종배경하량、악성결절유일정적진단개치。
Objective To evaluate the application of contrast- enhanced ultrasonography (CEUS) in differential diagnosis between benign and malignant thyroid nodules in patients with nodular goiter. Methods One hundred and five suspected thy-roid nodules in patients with the nodular goiter were examined by CEUS. The enhanced characteristics of the nodules were ana-lyzed and the pathological diagnosis was obtained from surgical y resected nodules. Results The dominant enhanced pattern was isoenhancement for benign thyroid nodules (39.5%, 15/38) and hypoenhancement for the malignant one (44.8%, 30/67) re-spectively. There was significant difference of the enhanced pattern between benign and malignant nodules(P<0.05). Most of the nodules appeared as heterogeneous enhancement both in benign(60.5%) or malignant (68.7%) ones. Most of the malignant nod-ules (62.7%, 42/67) presented "wash- in slowly"and "wash- out simultaneously"signs, whereas 50% of the benign nodules ap-peared as"wash- in simultaneously"and"wash- out simultaneously"signs(P<0.01). Conclusion CEUS is valuable in the diagno-sis of benign and malignant thyroid nodules in patients with nodular goiter.