CAJ | 학술논문

　　目的研究乳腺癌患者血清中CEA、CA125、CA153的水平及其与生活质量的相关性。方法选择乳腺癌患者作为观察组、乳腺良性疾病患者作为良性对照组、健康体检者作为健康对照组，检测外周血中CEA、CA125、CA153的含量并观察生活质量相关指标。结果观察组患者CEA、CA125、CA153水平以及躯体功能、心理功能、社会功能、认知功能、总体生活质量评分明显高于良性对照组和健康对照组；躯体功能、心理功能、社会功能、认知功能、总体生活质量评分与CEA、CA125、CA153水平呈负相关。结论CEA、CA125、CA153检查对乳腺癌的诊断具有积极的临床价值，且与生活质量密切相关。
　　목적연구유선암환자혈청중CEA、CA125、CA153적수평급기여생활질량적상관성。방법선택유선암환자작위관찰조、유선량성질병환자작위량성대조조、건강체검자작위건강대조조，검측외주혈중CEA、CA125、CA153적함량병관찰생활질량상관지표。결과관찰조환자CEA、CA125、CA153수평이급구체공능、심리공능、사회공능、인지공능、총체생활질량평분명현고우량성대조조화건강대조조；구체공능、심리공능、사회공능、인지공능、총체생활질량평분여CEA、CA125、CA153수평정부상관。결론CEA、CA125、CA153검사대유선암적진단구유적겁적림상개치，차여생활질량밀절상관。
Objective To study the level of CEA,CA125,CA153 in breast cancer patients and its correlation with quality of life. Methods the breast cancer patients were selected as observation group,benign breast disease patients as benign control group, and healthy people as healthy control group,the peripheral blood levels of CEA,CA125, CA153 were detected and quality of life were observed. Results The CEA,CA125,CA153 levels and physical function,psychological function,social function,cognitive function,overall quality of life scores of observation group were significantly higher than benign control group and healthy control group;physical function,psychological function,social function,cognitive function,overall quality of life score were negatively correlated with CEA,CA125,CA153 levels. Conclusion The clinical value of positive CEA,CA125,CA153 examination in the diagnosis of breast cancer,which is closely related with the quality of life.