CAJ | 학술논문

　　目的探讨术前应用氟比洛芬酯和罗哌卡因在腹腔镜胆囊切除术后的镇痛效果。方法选择我院腹腔镜胆囊切除术后患者154例，根据麻醉方法不同分为对照组与观察组。对照组77例，观察组77例，观察组术前静注氟比洛芬酯，对照组术前局部注射罗哌卡因。采用视觉模拟评分，比较两组2、4、8、12、24 h 疼痛评分和镇痛评分及给予镇痛药后不良反应的比较。结果观察组术后2、4、8、12、24 h的疼痛评分和镇痛评分（2.7±0.5）、（2.8±1.2）、（2.9±1.8）、（2.2±0.7）、（1.6±0.5），均明显低于对照组，差异有统计学意义（P＜0.05）；观察组的镇痛药给予后不良反应总发生率22.07%，明显低于对照组，差异有统计学意（P＜0.05）。结论在腹腔镜胆囊切除术后的镇痛效果中，氟比洛芬酯比罗哌卡因的镇痛效果更好，不良反应发生率更低，值得临床推广使用。
　　목적탐토술전응용불비락분지화라고잡인재복강경담낭절제술후적진통효과。방법선택아원복강경담낭절제술후환자154례，근거마취방법불동분위대조조여관찰조。대조조77례，관찰조77례，관찰조술전정주불비락분지，대조조술전국부주사라고잡인。채용시각모의평분，비교량조2、4、8、12、24 h 동통평분화진통평분급급여진통약후불량반응적비교。결과관찰조술후2、4、8、12、24 h적동통평분화진통평분（2.7±0.5）、（2.8±1.2）、（2.9±1.8）、（2.2±0.7）、（1.6±0.5），균명현저우대조조，차이유통계학의의（P＜0.05）；관찰조적진통약급여후불량반응총발생솔22.07%，명현저우대조조，차이유통계학의（P＜0.05）。결론재복강경담낭절제술후적진통효과중，불비락분지비라고잡인적진통효과경호，불량반응발생솔경저，치득림상추엄사용。
Objective To investigate the analgesic effects of the preoperative application of flurbiprofen axetil and ropivacaine after the laparoscopic cholecystectomy. Methods 154 patients who had received laparoscopic cholecystectomy in our hospital were selected and divided into the control group and the observation group according to the anesthetic method. The control group contained 77 patients and the observation group contained 77 patients. The observation group received preoperative intravenous infusion of flurbiprofen axetil and the control group received preoperative local injection of ropivacaine. Using the visual analog scale, the 2, 4, 8, 12 and 24-hour pain scores and analgesia scores and the post-analgesic adverse reactions of the two groups were compared. Results The 2, 4, 8, 12 and 24-hour pain scores and analgesia scores of the observation group were (2.7±0.5), (2.8±1.2), (2.9±1.8), (2.2±0.7) and (1.6±0.5), which were significantly lower than those of the control group, with statistically significant differences (P < 0.05). The total incidence of adverse reactions of the observation group was 22.07%, which was significantly lower than that of the control group, with statistically significant differences (P<0.05). Conclusion In terms of the analgesic effect after the laparoscopic cholecystectomy, flurbiprofen axetil is better than ropivacaine and has lower incidence of adverse reactions, thereby worthy of clinical promotion and application.