CAJ | 학술논문

　　目的分析食管支架置入术联合三维适形放疗（3D-CRT）治疗中晚期食管癌的临床疗效。方法29例中晚期食管癌患者前期进行支架置入解决吞咽困难，后期针对原发病灶实施3D-CRT治疗(治疗组)，分析肿瘤局部控制率、生存率并与同期19例单纯支架治疗患者（对照组）进行对比研究。结果治疗组CR 5例（17.24%），PR 20例（68.97%），近期有效率（CR+PR）为86.21%。平均生存期为（13.13±1.00）个月，中位生存期为（12.50±1.08）个月，对照组平均生存期为（7.87±0.98）个月，中位生存期为（7.00±0.70）个月，两组生存率比较差异有统计学意义（P＜0.05)。结论支架置入术结合放疗治疗晚期食管癌有利于改善患者生活质量，提高患者生存率，是晚期食管癌的一种有效治疗方法。
　　목적분석식관지가치입술연합삼유괄형방료（3D-CRT）치료중만기식관암적림상료효。방법29례중만기식관암환자전기진행지가치입해결탄인곤난，후기침대원발병조실시3D-CRT치료(치료조)，분석종류국부공제솔、생존솔병여동기19례단순지가치료환자（대조조）진행대비연구。결과치료조CR 5례（17.24%），PR 20례（68.97%），근기유효솔（CR+PR）위86.21%。평균생존기위（13.13±1.00）개월，중위생존기위（12.50±1.08）개월，대조조평균생존기위（7.87±0.98）개월，중위생존기위（7.00±0.70）개월，량조생존솔비교차이유통계학의의（P＜0.05)。결론지가치입술결합방료치료만기식관암유리우개선환자생활질량，제고환자생존솔，시만기식관암적일충유효치료방법。
Objective To evaluate the efficacy of esophageal stent inserting combined with three-dimensional conformal radiotherapy(3D-CRT) in the treatment of locally advanced esophageal carcinoma. Methods Twenty-nine patients of advanced esophageal carcinoma were inserted stent to solve the esophageal stenosis first,and then were applied with 3D-CRT(treated group).The efficacy and the survival rate were analyzed and correlated with 19 patients who treated with stent placement alone (control group). Results In the study group,5 cases were observed as complete response (17.24%),20 cases were partial response (68.97%), the overall response rate was 86.21%.The mean survival time was(13.13±1.00)months,the median survival time was (12.50±1.08) months, compared with( 7.87±0.98) and(7.00±0.70)months of the control group,giving a significant difference between the two groups (P < 0.05). Conclusion The combination of stent placement and 3D-CRT improve the quality of life and survival rate markedly,it is an effective treatment for esophageal carcinoma.