中国医疗前沿
中國醫療前沿
중국의료전연
CHINA HEALTHCARE INNOVATION
2013年
14期
100-101
,共2页
f/tPSA%诊断灰区%前列腺癌
f/tPSA%診斷灰區%前列腺癌
f/tPSA%진단회구%전렬선암
f/tPSA%Diagnoses Gray Zone%Prostate Cancer
目的研究游离前列腺特异性抗原(fPSA)及总前列腺特异性抗原(tPSA)的比值(f/tPSA)对前列腺癌(PCa)鉴别诊断的价值。方法检测fPSA与tPSA并算出比值f/tPSA；同时算出不同f/tPSA所对应的特异性和敏感性。结果在4-10ng/ml的诊断灰区，PCa组与前列腺增生(BPH)组间血清中fPSA和tPSA的水平均无显著差异，而f/tPSA比值，PCa组(0.12±0.05)和BPH组(0.28±0.09)间差异显著(P<0.001)。结论在诊断灰区对前列腺癌的鉴别诊断，用f/tPSA比值比单独用tPSA及fPSA更有价值，诊断鉴别点以f/tPSA<0.19较为合适。
目的研究遊離前列腺特異性抗原(fPSA)及總前列腺特異性抗原(tPSA)的比值(f/tPSA)對前列腺癌(PCa)鑒彆診斷的價值。方法檢測fPSA與tPSA併算齣比值f/tPSA；同時算齣不同f/tPSA所對應的特異性和敏感性。結果在4-10ng/ml的診斷灰區，PCa組與前列腺增生(BPH)組間血清中fPSA和tPSA的水平均無顯著差異，而f/tPSA比值，PCa組(0.12±0.05)和BPH組(0.28±0.09)間差異顯著(P<0.001)。結論在診斷灰區對前列腺癌的鑒彆診斷，用f/tPSA比值比單獨用tPSA及fPSA更有價值，診斷鑒彆點以f/tPSA<0.19較為閤適。
목적연구유리전렬선특이성항원(fPSA)급총전렬선특이성항원(tPSA)적비치(f/tPSA)대전렬선암(PCa)감별진단적개치。방법검측fPSA여tPSA병산출비치f/tPSA；동시산출불동f/tPSA소대응적특이성화민감성。결과재4-10ng/ml적진단회구，PCa조여전렬선증생(BPH)조간혈청중fPSA화tPSA적수평균무현저차이，이f/tPSA비치，PCa조(0.12±0.05)화BPH조(0.28±0.09)간차이현저(P<0.001)。결론재진단회구대전렬선암적감별진단，용f/tPSA비치비단독용tPSA급fPSA경유개치，진단감별점이f/tPSA<0.19교위합괄。
Objective Research on the differential diagnostic value for prostate cancer(PCa) of the free PSA and total PSA ratio. Methods Detection of fPSA and tPSA and calculation of the ratio; and Calculates of the correspondent sensitivity and specificity of different f/tPSA. Results There is no significant difference between Pca group and BPH group in fPSA and tPSA, on the contrary, there is very significant difference between Pca group(0.12±0.05) and BPH group(0.28±0.09) in f/tPSA(P<0.001) in the diagnoses gray zone between 4-10ng/ml. Conclusion In the diagnoses gray zone, it is more effective to differentiate diagnose prostate cancer by means of f/tPSA ratio than by means of tPSA and fPSA, and it is more suitable to treat f/tPSA<0.19 as the diagnosis differentiation spot.
