CAJ | 학술논문

　　目的：观察不同血糖基础的血液病患者使用糖皮质激素（GC）治疗前后的血糖变化特点，探讨其临床意义。方法：65例血液病患者按OGTT分组为糖调节正常（NGT）、糖耐量异常（IGT）和糖尿病（DM）三组，观察各组患者使用GC治疗前后的血糖变化特点。结果：GC治疗后所有患者日平均血糖升高，且餐后血糖升高明显，GC治疗后三组间三餐前后各点血糖值比较差异有统计学意义（P<0.05）。结论：GC治疗后大部分患者的血糖都会升高，且GC所致血糖变化具有其自身特点，大部分患者表现为午后至睡前严重高血糖，部分患者可出现夜间低血糖。
　　목적：관찰불동혈당기출적혈액병환자사용당피질격소（GC）치료전후적혈당변화특점，탐토기림상의의。방법：65례혈액병환자안OGTT분조위당조절정상（NGT）、당내량이상（IGT）화당뇨병（DM）삼조，관찰각조환자사용GC치료전후적혈당변화특점。결과：GC치료후소유환자일평균혈당승고，차찬후혈당승고명현，GC치료후삼조간삼찬전후각점혈당치비교차이유통계학의의（P<0.05）。결론：GC치료후대부분환자적혈당도회승고，차GC소치혈당변화구유기자신특점，대부분환자표현위오후지수전엄중고혈당，부분환자가출현야간저혈당。
Objective:To investigate the characteristics of daily blood glucose profiles of patients with Hematonosis with glucocorticoid(CG) therapy.Method:65 patients with hematological diseases were divided into normal blood glucose group NGT(normal glucose tolerance),IGT(impaired glucose tolerance)and DM(diabetes mellitus)three groups with OGTT,the blood glucose levels of patients were characterized using GC before and after treatment.Result:Average level of daily blood glucose was higher after GC therapy,especially postprandial blood glucose.The significant difference was found in average level of blood glucose in three groups after GC therapy(P<0.05).Conclusion:After glucocorticoid treatment most of the patient’s blood glucose will rise,and the change of glucocorticoid induced by glucose has its own characteristics,and most of the patients showed server hyperglycemia afternoon to bedtime,partial patient can appear nocturnal hypoglycemia.