医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
22期
24-25
,共2页
人乳头瘤病毒(HPV)%基因分型
人乳頭瘤病毒(HPV)%基因分型
인유두류병독(HPV)%기인분형
Human papil oma virus ( HPV)%Genotyping
目的研究宁德地区女性人乳头瘤病毒(HPV)感染情况、基因分型特点。方法采用PCR和导流杂交技术对2463例女性HPV的21种亚型进行分型检测。结果该地区妇女HPV感染率为45.5%,21种HPV亚型均有检出,其中检出率较高的高危型有HPV16(12.2%)、HPV58(10.2%)、HPV52(9.3%);检出率较高的低危型HPVCP8304(4.6%)、HPV6(2.2%)。结论宁德地区女性HPV感染率45.5%与其他地区存在一定的差异,感染的优势型别为HPV16。
目的研究寧德地區女性人乳頭瘤病毒(HPV)感染情況、基因分型特點。方法採用PCR和導流雜交技術對2463例女性HPV的21種亞型進行分型檢測。結果該地區婦女HPV感染率為45.5%,21種HPV亞型均有檢齣,其中檢齣率較高的高危型有HPV16(12.2%)、HPV58(10.2%)、HPV52(9.3%);檢齣率較高的低危型HPVCP8304(4.6%)、HPV6(2.2%)。結論寧德地區女性HPV感染率45.5%與其他地區存在一定的差異,感染的優勢型彆為HPV16。
목적연구저덕지구녀성인유두류병독(HPV)감염정황、기인분형특점。방법채용PCR화도류잡교기술대2463례녀성HPV적21충아형진행분형검측。결과해지구부녀HPV감염솔위45.5%,21충HPV아형균유검출,기중검출솔교고적고위형유HPV16(12.2%)、HPV58(10.2%)、HPV52(9.3%);검출솔교고적저위형HPVCP8304(4.6%)、HPV6(2.2%)。결론저덕지구녀성HPV감염솔45.5%여기타지구존재일정적차이,감염적우세형별위HPV16。
Objective To evaluate the infection and genotype distribution of human papil oma virus (HPV) in Ningde region. Methods The PCR and flow-through hybridization was used to detect HPV genotype in 2463 cases of women. Result The infection rate of HPV among these women was 45.5% , the types of 21 kinds of HPV genotypes have been detected ,the top three high risk genotypes were HPV16(12.2%)、HPV58(10.2%)、HPV52(9.3%);and the highest low risk genotypes were HPVCP8304(4.6%)、HPV6(2.2%). Conclusion The infection rate of HPV among these women in Ningde region was 45.5% , which was different from other regions. HPV16 is the main genotype.