CAJ | 학술논문

　　目的分析轻度胃肠炎伴发婴幼儿良性惊厥（BICE）的临床特点及预后。方法对2008年2月-2012年2月住院治疗的轻度胃肠炎伴婴幼儿良性惊厥的患儿进行临床观察，病愈后进行4～52个月的随访，进一步明确诊断，回顾性分析其临床特点及预后。结果发病年龄最小6个月，最大35个月；男女比例9∶13；冬季发病l 7例，秋季发病25例，其他季节2例。腹泻第1天出现惊厥11例，腹泻第2天出现惊厥17例，腹泻第3天出现惊厥14例，腹泻第4天出现惊厥2例。44例患儿中39例为全身性强直阵挛发作；5例为部分性发作，惊止后未行抗癫痫治疗。发作间期脑电图(EEG)4例轻度异常，1例示不正常脑电图。脑脊液检查正常。头颅CT正常。神经系统查体1例巴宾斯基征阳性。8/43例粪便轮状病毒抗原阳性。粪常规正常。血生化未见明显异常。肝肾功能正常。随访4例复发，其中1例热性惊厥1次，无病例转化为癫痫。结论 BICE预后良好，不需要长期抗惊厥治疗。
　　목적분석경도위장염반발영유인량성량궐（BICE）적림상특점급예후。방법대2008년2월-2012년2월주원치료적경도위장염반영유인량성량궐적환인진행림상관찰，병유후진행4～52개월적수방，진일보명학진단，회고성분석기림상특점급예후。결과발병년령최소6개월，최대35개월；남녀비례9∶13；동계발병l 7례，추계발병25례，기타계절2례。복사제1천출현량궐11례，복사제2천출현량궐17례，복사제3천출현량궐14례，복사제4천출현량궐2례。44례환인중39례위전신성강직진련발작；5례위부분성발작，량지후미행항전간치료。발작간기뇌전도(EEG)4례경도이상，1례시불정상뇌전도。뇌척액검사정상。두로CT정상。신경계통사체1례파빈사기정양성。8/43례분편륜상병독항원양성。분상규정상。혈생화미견명현이상。간신공능정상。수방4례복발，기중1례열성량궐1차，무병례전화위전간。결론 BICE예후량호，불수요장기항량궐치료。
Objective To analyze the clinical characteristics and prognosis in patients of benign infantile convulsions with mild gastroenteritis(BICE). Methods Evaluated the clinical manifestations of 44 patients who hospitalized from February 2008 to February 2012,and then followed for 4 months to 52 months follow-up results to further clarify the diagnosis,retrospective analysis of clinical features and prognosis.Results The age of onset of minimum 6 months, maximum 35 months;the ratio of male to female was 9:13;l 7 cases in winter , 25 cases in fall and 2 cases of the other seasons.Convulsions occurred in 11 patients (25%) on the ifrst day,17 patients(38.6%)on the second day,14 patients(31.8%)on the third day and 2 patients(2.3%)on the forth day;35 children had generalised seizures and 5 had partial seizures.The interictal EEG was mildly abnormal in 4 patients and 1 abnormal.CSF examination were normal,All patients were normal with head CT imaging.1 abnormal of Brudzinski sign. 8/43 patients were positive for rotavirus.Stool test、Biochemical tests、Liver as well as kidney function detection were normal.During the follow up,4 children sufered from recurrence of BICE,1 sufered from simple febrile seizures,and no cases developed into epilepsy.Conclusion Prognosis can have a good effect on patients with BICE.So it is not necessary for the child to receive long-term antiepileptic therapy.