中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
12期
1079-1081
,共3页
甲状腺肿瘤%外科手术%预后
甲狀腺腫瘤%外科手術%預後
갑상선종류%외과수술%예후
Thyroid neoplasms%Surgical procedure,operative%Prognosis
目的 探讨老年甲状腺癌患者的手术治疗方法及影响预后的因素.方法 回顾性分析2001年1月至2010年12月我院近10年收治的96例60岁以上老年甲状腺癌患者的手术治疗情况及预后因素.采用Kaplan-Meier法计算生存率,预后相关单因素分析采用Log-rank检验,多因素分析采用Cox模型.结果 96例老年甲状腺癌患者的5年累积生存率为73.6％,中位生存时间为68个月.单因素分析结果显示:性别、年龄、淋巴结转移、远处转移、临床分期、肿瘤侵犯程度、同行改良颈淋巴结清扫术是预后影响因素(P＜0.05).多因素分析结果显示,年龄、临床分期、肿瘤侵犯程度及远处转移是影响老年甲状腺癌患者预后的独立因素(P＜0.05).结论 老年甲状腺癌患者预后较差,年龄、临床分期、肿瘤侵犯程度及远处转移是影响预后的独立重要因素,需要对老年患者预后做正确评估并制定个体化手术方案.
目的 探討老年甲狀腺癌患者的手術治療方法及影響預後的因素.方法 迴顧性分析2001年1月至2010年12月我院近10年收治的96例60歲以上老年甲狀腺癌患者的手術治療情況及預後因素.採用Kaplan-Meier法計算生存率,預後相關單因素分析採用Log-rank檢驗,多因素分析採用Cox模型.結果 96例老年甲狀腺癌患者的5年纍積生存率為73.6％,中位生存時間為68箇月.單因素分析結果顯示:性彆、年齡、淋巴結轉移、遠處轉移、臨床分期、腫瘤侵犯程度、同行改良頸淋巴結清掃術是預後影響因素(P＜0.05).多因素分析結果顯示,年齡、臨床分期、腫瘤侵犯程度及遠處轉移是影響老年甲狀腺癌患者預後的獨立因素(P＜0.05).結論 老年甲狀腺癌患者預後較差,年齡、臨床分期、腫瘤侵犯程度及遠處轉移是影響預後的獨立重要因素,需要對老年患者預後做正確評估併製定箇體化手術方案.
목적 탐토노년갑상선암환자적수술치료방법급영향예후적인소.방법 회고성분석2001년1월지2010년12월아원근10년수치적96례60세이상노년갑상선암환자적수술치료정황급예후인소.채용Kaplan-Meier법계산생존솔,예후상관단인소분석채용Log-rank검험,다인소분석채용Cox모형.결과 96례노년갑상선암환자적5년루적생존솔위73.6％,중위생존시간위68개월.단인소분석결과현시:성별、년령、림파결전이、원처전이、림상분기、종류침범정도、동행개량경림파결청소술시예후영향인소(P＜0.05).다인소분석결과현시,년령、림상분기、종류침범정도급원처전이시영향노년갑상선암환자예후적독립인소(P＜0.05).결론 노년갑상선암환자예후교차,년령、림상분기、종류침범정도급원처전이시영향예후적독립중요인소,수요대노년환자예후주정학평고병제정개체화수술방안.
Objective To investigate the surgical treatment and prognostic factors in elderly patients with thyroid cancer.Methods The surgical treatment and prognostic factors of 96 patients over the age of 60 years with thyroid cancer were analyzed retrospectively in our hospital from January 2001 to December 2010.The Kaplan-Meier method was applied to analyze survival rates,Log-rank test was used in the univariate analysis and multivariate Cox model was applied for the independent prognostic factors analysis.Results The 5 year survival for elderly patients was 73.6％ and median survival time was 68 months.Univariate analysis indicated that sex,age,lymph node metastases,distant metastasis,clinical stage,extent of tumor invasion and modified cervical lymph node dissection were prognostic factors (all P＜0.05).Multivariate analysis showed that age,clinical stage,extent of tumor invasion and distant metastasis were independent prognostic factors(P＜0.05).Conclusions The elderly patients with thyroid cancer are in poor prognosis.Age,clinical stage,extent of tumor invasion and distant metastasis are independent important prognostic factors.Individualized surgical treatment should be made on the basis of correct assessment of prognosis.
