CAJ | 학술논문

目的探讨喹硫平与利培酮对女性精神分裂症患者血清催乳素和体重指数BMI的影响.方法选取未用药或停药1月的100例女性精神分裂症患者,随机分为喹硫平组和利培酮组治疗,分别给予喹硫平与利培酮单独治疗12周.在治疗前后分别测定血清催乳素水平和体重,计算体重指数BMI.结果治疗12周后喹硫平组血清催乳素和体重指数BMI无明显增加,利培酮组则显著增加,体重指数BMI和催乳素水平变化呈正相关.结论喹硫平对女性患者催乳素和体重BMI指数无明显影响,利培酮对女性患者催乳素和体重指数BMI影响明显.
목적 탐토규류평여리배동대녀성정신분렬증환자혈청최유소화체중지수BMI적영향.방법 선취미용약혹정약1월적100례녀성정신분렬증환자,수궤분위규류평조화리배동조치료,분별급여규류평여리배동단독치료12주.재치료전후분별측정혈청최유소수평화체중,계산체중지수BMI.결과 치료12주후규류평조혈청최유소화체중지수BMI무명현증가,리배동조칙현저증가,체중지수BMI화최유소수평변화정정상관.결론 규류평대녀성환자최유소화체중BMI지수무명현영향,리배동대녀성환자최유소화체중지수BMI영향명현.
Objective To investigate the influence of quetiapine and risperdal on the serum prolactin levels and body mass index (BMI) of female patients with schizophrenic.Methods 100 female schizophrenic patients,who had never used medication or had discontinued medication for a month,were randomly divided into two groups,the quetiapine group and the risperdal group.Each group was provided with quetiapine or risperdal,respectively,for 12 weeks.The serum prolactin level and body weight were recorded and BMI was calculated for each patient,before and after the treatment.Results After 12 weeks of treatment,the serum prolactin level and BMI in the quetiapine group had no significant increase,while they increased significantly in the risperidone group.It also showed that BMI and serum prolactin level changes had positive correlation.Conclusion Risperdal has significant effect on the serum prolactin and BMI of female schizophrenic patients,but quetiapine has not.