CAJ | 학술논문

目的应用动物模型评估保留残端对兔前交叉韧带(ACL)重建的生物力学意义. 方法将50只成年健康新西兰大白兔一侧后肢制作ACL断裂模型后随机分为两组(n=25),一组行保留残端ACL重建术(保残组),另一组行去除残端ACL重建术(去残组).所有手术均采用自体半腱肌腱作为移植物,并于术后12周统一将两组动物处死,行ACL大体观察及生物力学测试. 结果术后12周取材时,保残组和去残组总计50个标本关节活动度与正常侧相比差异无统计学意义(t=0.440,P＝0.662).所有ACL移植物连续性完整,张力满意.保残组和去残组标本屈膝30°与90°胫骨前移距离、最大拉力载荷、最大拉伸距离以及刚度所占正常侧百分比差异均无统计学意义(P＞0.05)；保残组中残端存活组和残端失效组标本屈膝30°与90°胫骨前移距离、最大拉力载荷、最大拉伸距离以及刚度所占正常侧百分比差异均无统计学意义(P＞ 0.05). 结论保留残端重建ACL不能显著提高术后兔ACL的生物力学性能.
목적 응용동물모형평고보류잔단대토전교차인대(ACL)중건적생물역학의의. 방법 장50지성년건강신서란대백토일측후지제작ACL단렬모형후수궤분위량조(n=25),일조행보류잔단ACL중건술(보잔조),령일조행거제잔단ACL중건술(거잔조).소유수술균채용자체반건기건작위이식물,병우술후12주통일장량조동물처사,행ACL대체관찰급생물역학측시. 결과 술후12주취재시,보잔조화거잔조총계50개표본관절활동도여정상측상비차이무통계학의의(t=0.440,P＝0.662).소유ACL이식물련속성완정,장력만의.보잔조화거잔조표본굴슬30°여90°경골전이거리、최대랍력재하、최대랍신거리이급강도소점정상측백분비차이균무통계학의의(P＞0.05)；보잔조중잔단존활조화잔단실효조표본굴슬30°여90°경골전이거리、최대랍력재하、최대랍신거리이급강도소점정상측백분비차이균무통계학의의(P＞ 0.05). 결론 보류잔단중건ACL불능현저제고술후토ACL적생물역학성능.
Objective To evaluate the biomechanical stability of the knee joint after remnant-preserved anterior cruciate ligament (ACL) reconstruction using a rabbit model.Methods Models of ACL rupture were created in any one of the hindlimbs of 50 mature female New Zealand white rabbits before the animals were randomly divided into 2 equal groups.Group 1 (n =25) were treated with remnant-preserved ACL reconstruction using semitendinosus tendon autografts and group 2(n =25) with conventional ACL reconstruction using semitendinosus tendon autografts.All animals were sacrificed at 12 weeks after surgery for macroscopic evaluations and biomechanical testing.Results Macroscopic observations revealed that there were no significant differences between the operated and normal hindlimbs regarding the rang of motion (ROM) (t =0.440,P =0.662).All reconstructed ACLs maintained adequate continuity and tension.The biomechanical testing showed no significant differences between the 2 groups with respect to the anterior translation at 30° and 90° of knee flexion,the elongation at failure and the ratio of the ultimate failure load and the stiffness compared to the normal side (P ＞ 0.05).In group 1,the specimens of surviving remnant fibers had no significant biomechanical differences from those of failed remnant fibers either with respect to the above indexes (P ＞0.05).Conclusion The remnant preservation technique may not significantly enhance the biomechanical performance of reconstructed ACLs in rabbits.