CAJ | 학술논문

背景接受心脏手术患者日益增加,而在心脏手术围术期的镇痛药物使用中,瑞芬太尼相对其他镇痛药物具有独特的优势,因此该药在心脏手术围术期中应用广泛. 目的对有关瑞芬太尼的论著进行归纳总结,阐述其在心脏手术围术期的应用进展. 内容瑞芬太尼具有独特的药物代谢动力学特点,加上其心血管的保护作用使之成为肝、肾或心功能不良患者的推荐用药.瑞芬太尼不仅在心脏手术中有对抗术中的应激刺激、加快术后恢复、提前脱离机械通气以及拔管时间等优势,也常用于心血管微创手术和经食管超声心动图等诊断性操作中.此外,瑞芬太尼可缩短心脏重症监护病房患者持续用药后气管拔管的时间. 趋势瑞芬太尼在心脏手术麻醉管理中的重要性已相当明确,其在心脏手术围术期中的地位也日益突出.
배경 접수심장수술환자일익증가,이재심장수술위술기적진통약물사용중,서분태니상대기타진통약물구유독특적우세,인차해약재심장수술위술기중응용엄범. 목적 대유관서분태니적론저진행귀납총결,천술기재심장수술위술기적응용진전. 내용 서분태니구유독특적약물대사동역학특점,가상기심혈관적보호작용사지성위간、신혹심공능불량환자적추천용약.서분태니불부재심장수술중유대항술중적응격자격、가쾌술후회복、제전탈리궤계통기이급발관시간등우세,야상용우심혈관미창수술화경식관초성심동도등진단성조작중.차외,서분태니가축단심장중증감호병방환자지속용약후기관발관적시간. 추세 서분태니재심장수술마취관리중적중요성이상당명학,기재심장수술위술기중적지위야일익돌출.
Background Remitentanil has been applied in more and more cardiac operation because of several advantages not observed in other analgesics.Objective Explain the role of remifentanil used in cardiac surgical during preoperative period by summarizing articles.Content Because of the unique pharmacokinetic profile and potential protective cardiac preconditioning effect,remifentanil is recommended even in patients with renal impairment,hepatic dysfunction or poor cardiovascular function.The potential benefits of remifentanil in cardiac surgery not only include protection against intraoperative stressful stimulus,but also rapid postoperative recovery,early weaning from mechanical ventilation,and extubation.Remifentanil has also been often applied in minimally invasive cardiol0gic techniques or diagnostic procedures such as transesophageal echocardiography as a ideal sedative agents.Remifentanil can reduce the time to tracheal extubation after cessation of the continuous infusion in ICU.Trend Remifentanil has been proved to be essential in anesthesia management of cardiac operation,and it will play a major role in cardiac surgical preoperative period.