CAJ | 학술논문

目的探讨单纯性结膜下出血患者与颈动脉内膜中层(IMT)厚度之间的关系.方法对2011年1月至2012年12月在上海市徐汇区大华医院眼科就诊的患者,选择单纯性结膜下出血者245例(245只眼)为出血组,208名(208只眼)健康体检者作为对照组,同时作颈动脉超声检查.结果单纯性结膜下出血患者IMT＜0.9 mm 68例,0.9 mm≤IMT＜1.2 mm 98例,IMT≥1.2 mm或颈动脉血管段存在突入管腔的回声,表面不光滑为颈动脉硬化斑块79例,根据IMT分布结果,所有入组对象中IMT≥0.9 mm组(177/260,68.08％)结膜下出血发病率明显高于IMT＜0.9 mm组(68/193,35.23％),差异有统计学意义(P＜0.01).Logistic回归显示IMT是单纯性结膜下出血的主要危险因素(P＜0.05).结论单纯性结膜下出血与颈动脉内膜中层增厚有一定相关性,提示临床上对单纯性结膜下出血患者应重视颈动脉IMT的检测.
목적 탐토단순성결막하출혈환자여경동맥내막중층(IMT)후도지간적관계.방법 대2011년1월지2012년12월재상해시서회구대화의원안과취진적환자,선택단순성결막하출혈자245례(245지안)위출혈조,208명(208지안)건강체검자작위대조조,동시작경동맥초성검사.결과 단순성결막하출혈환자IMT＜0.9 mm 68례,0.9 mm≤IMT＜1.2 mm 98례,IMT≥1.2 mm혹경동맥혈관단존재돌입관강적회성,표면불광활위경동맥경화반괴79례,근거IMT분포결과,소유입조대상중IMT≥0.9 mm조(177/260,68.08％)결막하출혈발병솔명현고우IMT＜0.9 mm조(68/193,35.23％),차이유통계학의의(P＜0.01).Logistic회귀현시IMT시단순성결막하출혈적주요위험인소(P＜0.05).결론 단순성결막하출혈여경동맥내막중층증후유일정상관성,제시림상상대단순성결막하출혈환자응중시경동맥IMT적검측.
Objective To explore the relation between patients with spontaneous subconjunctival hemorrhage and their carotid artery intima-media thickness (IMT).Methods 245 patients (245 eyes) who were diagnosed subconjunctival hemorrhage and 208 cases of general health check-up persons were collected.The age,gender,blood pressure,carotid Ultrasonography and site of subconjunctival hemorrhage were detected for all subjects.the correlation between subconjunctival hemorrhage and IMT were analyzed.Results 68 patients with simple subconjunctival hemorrhage of IMT＜0.9 mm,98 cases of 0.9mm≤IMT＜l.2mm,79 cases of IMT ≥1.2 mm or carotid arterial blood section is the echo of the lumen,and the surface is not smooth and of carotid atherosclerosis plaque.IMT≥ 0.9mm group(177/260,68.08％)was significantly higher than IMT＜0.9mm group (68/193,35.23％) in incidence rate of subconjunctival hemorrhage (P ＜0.01),Logistic regression shows that IMT is a major risk factor for simple subconjunctival hemorrhage (P ＜0.05).Conclusion there is some correlation of simple subconjunctival hemorrhage and thickening of the carotid artery intima-media,patients with simple subconjunctival hemorrhage should clinically pay attention to detection of carotid IMT