CAJ | 학술논문

目的：探讨缺血性脑卒中患者血尿酸（SUA）水平与脑动脉狭窄之间的关系。方法从收治的缺血性脑卒中患者中，随机选择经脑血管造影术确诊有脑动脉狭窄的患者186例、无狭窄患者42例。根据造影结果，将脑动脉狭窄分为轻度狭窄组74例，中度狭窄组66例和重度狭窄组46例。单支血管狭窄103例，多支血管狭窄83例。比较不同组别间SUA水平的差异以及SUA与脑动脉狭窄程度之间的关系。结果无狭窄患者SUA水平明显低于有狭窄患者（P＜0．05），轻度狭窄组SUA水平明显低于中度狭窄组（P＜0．05），中度狭窄组SUA水平低于重度狭窄组（P＜0．05）。脑动脉狭窄与血尿酸水平呈正相关（r＝0．413，P＜0．05），Logistic回归分析显示SUA并不是脑动脉狭窄的独立危险因素（P＝0．213）。结论 SUA水平与脑动脉狭窄呈正相关，但不是脑动脉狭窄的独立危险因素。
목적：탐토결혈성뇌졸중환자혈뇨산（SUA）수평여뇌동맥협착지간적관계。방법종수치적결혈성뇌졸중환자중，수궤선택경뇌혈관조영술학진유뇌동맥협착적환자186례、무협착환자42례。근거조영결과，장뇌동맥협착분위경도협착조74례，중도협착조66례화중도협착조46례。단지혈관협착103례，다지혈관협착83례。비교불동조별간SUA수평적차이이급SUA여뇌동맥협착정도지간적관계。결과무협착환자SUA수평명현저우유협착환자（P＜0．05），경도협착조SUA수평명현저우중도협착조（P＜0．05），중도협착조SUA수평저우중도협착조（P＜0．05）。뇌동맥협착여혈뇨산수평정정상관（r＝0．413，P＜0．05），Logistic회귀분석현시SUA병불시뇌동맥협착적독립위험인소（P＝0．213）。결론 SUA수평여뇌동맥협착정정상관，단불시뇌동맥협착적독립위험인소。
Objective To study the relationship between serum uric acid(SUA)level and cerebral artery stenosis in patients with ischemic stroke.Methods Patients with ischemic stroke were examined with subtraction and diagnosed as with(186)and without cerebral artery stenosis(42).Patients with stenosis were further grouped as slight(74),moderate(66),and severe stenosis(46).There were 103 pa-tients with single stenosis and 83 patients with dual cerebral artery stenosis.The serum uric acid levels of the groups patients were researched. Results The level of SUA was significantly lower in patients without than in patients with cerebal artery stenosis(P<0.01);SUA was sig-nificantly lower in patient with mild stenosis than in patients with moderate stenosis(P<0.05);significantly lower in patients with moderate stenosis than in patients with severe stenosis(P<0.05).Spearman rank correlation analysis showed that SUA level and the degree of cerebral artery stenosis was positively correlated(r=0.413,P<0.01).Logistic regression analysis showed that SUA level was not an independent risk factor of cerebral artery stenosis(P=0.213).Conclusion There is correlation between SUA level and the severity of the cerebral artery ste-nosis,but SUA level is not an independent risk factor for cerebral artery stenosis.