CAJ | 학술논문

目的：观察碱性成纤维细胞生长因子（bFGF）辅助点阵铒激光治疗面部凹陷性痤疮瘢痕的治疗效果和安全性。方法选取64例面部凹陷性痤疮瘢痕的患者，采用点阵铒激光治疗后分成两组。观察组面部冰敷胶原贴敷料并喷洒bFGF ，对照组仅面部冰敷胶原贴敷料，两组连续治疗10 d。术后观察创面愈合时间、不良反应，治疗前后以ECCA权重评分表对瘢痕进行评分，并统计患者满意率。结果两组创面均Ⅰ期愈合，观察组创面平均愈合时间7．2d，对照组创面平均愈合时间10．4d，两组比较差异有统计学意义（ P＜0．05）。对所有患者在治疗结束3个月后进行随访，两组瘢痕均有不同程度改善，有效率100％。结论点阵铒激光联合bFGF是治疗面部凹陷性痤疮瘢痕安全且有效的治疗方法。
목적：관찰감성성섬유세포생장인자（bFGF）보조점진이격광치료면부요함성좌창반흔적치료효과화안전성。방법선취64례면부요함성좌창반흔적환자，채용점진이격광치료후분성량조。관찰조면부빙부효원첩부료병분쇄bFGF ，대조조부면부빙부효원첩부료，량조련속치료10 d。술후관찰창면유합시간、불량반응，치료전후이ECCA권중평분표대반흔진행평분，병통계환자만의솔。결과량조창면균Ⅰ기유합，관찰조창면평균유합시간7．2d，대조조창면평균유합시간10．4d，량조비교차이유통계학의의（ P＜0．05）。대소유환자재치료결속3개월후진행수방，량조반흔균유불동정도개선，유효솔100％。결론점진이격광연합bFGF시치료면부요함성좌창반흔안전차유효적치료방법。
Objective To observe the effect and safety of bFGF auxiliary fractional Er :YAG laser in the treatment of facial a-trophic acne scar .Methods After fractional Er :YAG laser treatment ,64 cases of facial atrophic acne scar patients were randomly divided into two groups ,the observation group was applied facial ice collagen dressing and sprayed fibroblast growth factor ,the con-trol group was only applied facial ice collagen dressing .Treatment in two groups last for 10 consecutive days .Postoperative to ob-serve the wound healing time ,adverse reactions ,using B .Dreno′s ECCA grading scale to identify and quantify facial atrophic scars before and after treatment and statistics the satisfactory rate of patients .Results The wounds of two groups were conventional healing ,in the observation group the average healing time was 7 .2 days ,and that of control group was 10 .4 days ,there was signifi-cant difference (P<0 .05) .For all patients at the end of treatment and followed-up 3 months later ,scar were all improved ,with an efficiency of 100% .Conclusion Fractional Er :YAG laser combined with bFGF is a safe and effective treatment method for treat-ment of facial atrophic acne scars .