CAJ | 학술논문

甘草次酸是甘草的主要活性成分。近年来对甘草次酸及其生物药理作用的研究不断深入，逐渐明确其药理作用，它具有抗炎、抗氧化、抗肿瘤、抗菌、抗病毒等多种作用。就抗炎来说，甘草次酸及其衍生物可以通过多个靶点直接抑制炎性细胞因子和炎性介质的产生，也可以通过增强类固醇激素的活性等机制间接地发挥其抗炎功能。本文结合近年来国内外的研究现状对甘草次酸及衍生物的抗炎作用进行综述。
감초차산시감초적주요활성성분。근년래대감초차산급기생물약리작용적연구불단심입，축점명학기약리작용，타구유항염、항양화、항종류、항균、항병독등다충작용。취항염래설，감초차산급기연생물가이통과다개파점직접억제염성세포인자화염성개질적산생，야가이통과증강류고순격소적활성등궤제간접지발휘기항염공능。본문결합근년래국내외적연구현상대감초차산급연생물적항염작용진행종술。
Glycyrrhetinic acid ( GA) is extracted from the roots of licorice plants .GA serves as a herbal medicine with a wide range of applications .Anti-inflammatory, anti-diabetic, antioxidant, anti-tumor, antimicrobial and anti -viral properties of GA have been reported .Glycyrrhetinic acid and its derivatives could either directly inhibit inflammatory cyto-kines or enhance the function of steroid hormone indirectly alleviating inflammation .This review elaborates the anti -in-flammatory effects of glycyrrhetinic acid and its derivatives .