中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
13期
1975-1977
,共3页
支原体,肺%哮喘%免疫球蛋白E%白细胞介素5
支原體,肺%哮喘%免疫毬蛋白E%白細胞介素5
지원체,폐%효천%면역구단백E%백세포개소5
Mycoplasma pulmonis%Asthma%Immunoglobulin E%Interleukin-5
目的 探讨免疫球蛋白E(IgE)及白细胞介素5(IL-5)在肺炎支原体感染合并支气管哮喘患儿诊断中的临床意义.方法 选择住院治疗的肺炎支原体感染合并支气管哮喘患儿40例为观察组,另选择肺炎支原体感染未合并支气管哮喘患儿40例为对照组,所有患儿均在入院次日清晨抽取空腹静脉血检测IgE及IL-5水平.结果 观察组患儿血清总IgE水平为(335.74±38.84) IU/ml,IL-5水平为(311.86±35.28) ng/L,均显著高于对照组患儿(P＜0.05).经二分类Logistic回归分析,血清IgE与IL-5水平均差异有统计学意义(P＜0.05).结论 肺炎支原体感染合并支气管哮喘患儿IgE与IL-5水平升高更加明显,且血清IgE与IL-5水平是肺炎支原体感染合并支气管哮喘患儿发病的重要危险因素.
目的 探討免疫毬蛋白E(IgE)及白細胞介素5(IL-5)在肺炎支原體感染閤併支氣管哮喘患兒診斷中的臨床意義.方法 選擇住院治療的肺炎支原體感染閤併支氣管哮喘患兒40例為觀察組,另選擇肺炎支原體感染未閤併支氣管哮喘患兒40例為對照組,所有患兒均在入院次日清晨抽取空腹靜脈血檢測IgE及IL-5水平.結果 觀察組患兒血清總IgE水平為(335.74±38.84) IU/ml,IL-5水平為(311.86±35.28) ng/L,均顯著高于對照組患兒(P＜0.05).經二分類Logistic迴歸分析,血清IgE與IL-5水平均差異有統計學意義(P＜0.05).結論 肺炎支原體感染閤併支氣管哮喘患兒IgE與IL-5水平升高更加明顯,且血清IgE與IL-5水平是肺炎支原體感染閤併支氣管哮喘患兒髮病的重要危險因素.
목적 탐토면역구단백E(IgE)급백세포개소5(IL-5)재폐염지원체감염합병지기관효천환인진단중적림상의의.방법 선택주원치료적폐염지원체감염합병지기관효천환인40례위관찰조,령선택폐염지원체감염미합병지기관효천환인40례위대조조,소유환인균재입원차일청신추취공복정맥혈검측IgE급IL-5수평.결과 관찰조환인혈청총IgE수평위(335.74±38.84) IU/ml,IL-5수평위(311.86±35.28) ng/L,균현저고우대조조환인(P＜0.05).경이분류Logistic회귀분석,혈청IgE여IL-5수평균차이유통계학의의(P＜0.05).결론 폐염지원체감염합병지기관효천환인IgE여IL-5수평승고경가명현,차혈청IgE여IL-5수평시폐염지원체감염합병지기관효천환인발병적중요위험인소.
Objective To explore the clinical value of IgE and IL-5 in diagnosis of mycoplasma pneumoniae children with bronchial asthma.Methods 40 mycoplasma pneumoniae infection children complicated with bronchial asthma were chosen as the observation group,the other 40 mycoplasma pneumoniae infection children without bronchial asthma were selected as the control group.All children were admitted to hospital,the next morning fasting blood was obtained to detect IgE and IL-5 levels.Results The serum total IgE level of observation group was (335.74 ±38.84) IU/ml,the level of IL-5 was (311.86 ± 35.28) ng/L,which were significantly higher than control group (P ＜0.05).Binary Logistic regression analysis showed that,serum IgE level and IL-5 level had statistically significant difference (P ＜ 0.05).Conclusion Mycoplasma pneumoniae infection in children with bronchial asthma,the IgE and IL-5 levels increased more obviously,and the levels of serum IgE and IL-5 were important risk factors of onset of children with Mycoplasma pneumoniae infection combined bronchial asthma.
