中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2014年
1期
69-71
,共3页
呼吸道感染%降钙素%前白蛋白
呼吸道感染%降鈣素%前白蛋白
호흡도감염%강개소%전백단백
Respiratory tract infections%Procalcitonin%Prealbumin
目的：探讨血清降钙素原（PCT）和血清前清蛋白（PA）检测在呼吸道感染性疾病诊断中的临床价值。方法选取90例经呼吸内科确诊的细菌感染患者为观察组，另选48例健康体检者为对照组。PCT和PA检测分别采用免疫发光法和比色法，测定两组血清水平，并进行统计学分析。结果观察组患者PCT水平显著高于对照组（χ2=7.512，P=0.0046），而PA水平则低于对照组（χ2=7.126，P=0.0058）；观察组患者以上两项指标阳性率显著高于对照组（χ2=7.628，P=0.0047）。治疗1周后，观察组PCT水平显著降低，而PA水平显著升高，治疗前后差异具有统计学意义（χ2=3.629，P=0.034）。结论血清PCT和PA测定可作为呼吸道感染性疾病诊断和鉴别诊断的常规指标，对指导抗菌药物的合理使用，病情评估和疗效判断均具有重要的指导意义。
目的：探討血清降鈣素原（PCT）和血清前清蛋白（PA）檢測在呼吸道感染性疾病診斷中的臨床價值。方法選取90例經呼吸內科確診的細菌感染患者為觀察組，另選48例健康體檢者為對照組。PCT和PA檢測分彆採用免疫髮光法和比色法，測定兩組血清水平，併進行統計學分析。結果觀察組患者PCT水平顯著高于對照組（χ2=7.512，P=0.0046），而PA水平則低于對照組（χ2=7.126，P=0.0058）；觀察組患者以上兩項指標暘性率顯著高于對照組（χ2=7.628，P=0.0047）。治療1週後，觀察組PCT水平顯著降低，而PA水平顯著升高，治療前後差異具有統計學意義（χ2=3.629，P=0.034）。結論血清PCT和PA測定可作為呼吸道感染性疾病診斷和鑒彆診斷的常規指標，對指導抗菌藥物的閤理使用，病情評估和療效判斷均具有重要的指導意義。
목적：탐토혈청강개소원（PCT）화혈청전청단백（PA）검측재호흡도감염성질병진단중적림상개치。방법선취90례경호흡내과학진적세균감염환자위관찰조，령선48례건강체검자위대조조。PCT화PA검측분별채용면역발광법화비색법，측정량조혈청수평，병진행통계학분석。결과관찰조환자PCT수평현저고우대조조（χ2=7.512，P=0.0046），이PA수평칙저우대조조（χ2=7.126，P=0.0058）；관찰조환자이상량항지표양성솔현저고우대조조（χ2=7.628，P=0.0047）。치료1주후，관찰조PCT수평현저강저，이PA수평현저승고，치료전후차이구유통계학의의（χ2=3.629，P=0.034）。결론혈청PCT화PA측정가작위호흡도감염성질병진단화감별진단적상규지표，대지도항균약물적합리사용，병정평고화료효판단균구유중요적지도의의。
Objective To investigate the diagnosis siginificance of serum procalcitonin (PCT) and prealbumin (PA) in patients with bacterial respiratory tract infections. Methods Total of 90 patients with bacterial infection from department of respiratory medicine were enrolled as observation group and 48 cases of healthy as control group. The serum levels of PCT and PA of the two groups were detected by immuonluminescent assay and electrochemical method, respectively. Results The serum level of PCT in observation group was siginificantly higher than that in B group (χ2= 7.512, P= 0.0046), but with siginiifcantly lower level of PA (χ2=7.126, P=0.0058) and siginiifcantly higher positive rate of serum PCT and PA (χ2=7.62, P=0.0047). One week after treatment, the observation group had signiifcant reduction of PCT, and a signiifcant increase of PA, with signiifcant difference before and after treatment (χ2=3.62, P=0.034). Conclusions Serum levels of PCT and PA could be used as speciifc indicators of bacterial respiratory tract infections and with guilding siginiifcance for clinical diagnosis and treatment.
