中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
1期
88-90
,共3页
张方华%阎胜利%姚民秀%徐倩%王会玲%商永芳%李盈
張方華%閻勝利%姚民秀%徐倩%王會玲%商永芳%李盈
장방화%염성리%요민수%서천%왕회령%상영방%리영
甲巯咪唑%抗甲状腺药%关节炎综合征
甲巰咪唑%抗甲狀腺藥%關節炎綜閤徵
갑구미서%항갑상선약%관절염종합정
Methimazole%Antithyroid agents%Arthritis syndrome
目的：报道1例服用甲巯咪唑（商品名赛治）出现抗甲状腺综合征的患者，并进行文献复习。方法对1例30岁女性服用赛治出现抗甲状腺综合征患者的临床资料进行回顾性分析，并复习相关文献。结果本例患者因甲状腺功能亢进症口服赛治（10 mg，tid）治疗，25 d后出现游走性多关节疼痛、活动受限。停用赛治，口服洛索洛芬钠（商品名乐松）治疗，关节疼痛好转。换用丙硫氧嘧啶治疗，无不良反应。结论口服赛治可发生抗甲状腺关节炎综合征，需立即停药。
目的：報道1例服用甲巰咪唑（商品名賽治）齣現抗甲狀腺綜閤徵的患者，併進行文獻複習。方法對1例30歲女性服用賽治齣現抗甲狀腺綜閤徵患者的臨床資料進行迴顧性分析，併複習相關文獻。結果本例患者因甲狀腺功能亢進癥口服賽治（10 mg，tid）治療，25 d後齣現遊走性多關節疼痛、活動受限。停用賽治，口服洛索洛芬鈉（商品名樂鬆）治療，關節疼痛好轉。換用丙硫氧嘧啶治療，無不良反應。結論口服賽治可髮生抗甲狀腺關節炎綜閤徵，需立即停藥。
목적：보도1례복용갑구미서（상품명새치）출현항갑상선종합정적환자，병진행문헌복습。방법대1례30세녀성복용새치출현항갑상선종합정환자적림상자료진행회고성분석，병복습상관문헌。결과본례환자인갑상선공능항진증구복새치（10 mg，tid）치료，25 d후출현유주성다관절동통、활동수한。정용새치，구복락색락분납（상품명악송）치료，관절동통호전。환용병류양밀정치료，무불량반응。결론구복새치가발생항갑상선관절염종합정，수립즉정약。
Objective To report one case of taking thyrozol appears arthritis syndrome patients and a literature review. Methods A 30-year-old female patient with hyperthyroidism appeared arthritis syndrome after starting therapy with the antithyroid drug thyrozol.The patient clinical data were retrospectively analyzed, and review of the literature. Results The patient with hyperthyroidism due to oral thyrozol (10 mg tid) therapy 25 days, her joint happened the migratory joint pain, and limited mobility. Thyrozol was withdrawn.Symptoms disappeared after loxonin was given. Oral therapy was switched to propylthiouracil, no adverse reactions. Conclusion Antithyroid arthritis syndrome can occur when thyrozol therapy for hyperthyroidism. Prompt withdrawal of the antithyroid drug is necessary.
