CAJ | 학술논문

目的以数据分析软件拟合合肥地区孕中期母血清标志物中位数方程，并评价新方程的效果。方法取合肥地区33638例孕妇的产前筛查数据，以SPSS 17.0拟合新中位数方程，比较新中位数与2T-Risk软件内嵌中位数，计算风险结果，比较筛查效率。结果新中位数方程与内嵌中位数有差异，更换中位数后，筛查效率提高。结论用数据分析软件拟合本实验室中位数方程可以提高筛查效率，此中位数方程对合肥地区产前筛查有指导意义。
목적이수거분석연건의합합비지구잉중기모혈청표지물중위수방정，병평개신방정적효과。방법취합비지구33638례잉부적산전사사수거，이SPSS 17.0의합신중위수방정，비교신중위수여2T-Risk연건내감중위수，계산풍험결과，비교사사효솔。결과신중위수방정여내감중위수유차이，경환중위수후，사사효솔제고。결론용수거분석연건의합본실험실중위수방정가이제고사사효솔，차중위수방정대합비지구산전사사유지도의의。
Objective To detect the median equation of maternal serum markers with second trimester gestation in Hefei, and to evaluate the effect of the new equation. Methods The maternal serum markers of 33 638 women were involved in this study. The new median equation was calculated through SPSS 17.0 and the difference between new median and data of 2T-risk were also evaluated. The individual risk assessment was established to verify antep-artum risk screening results. Results The new median equation was superior to data of 2T-risk which effectively reduced the birth defects. Conclusion Screening efficiency can be improved by re-calculation of median, and the new median equation has very important significance to the prenatal screening in Hefei.