CAJ | 학술논문

目的：探讨婚姻状态与阴茎鳞状细胞癌（SCCP）患者的预后疗效关系。方法利用SEER数据库1988年至2009年诊断为SCCP的病例2681例。Logistic回归分析婚姻状态与肿瘤分期的关系。Cox回归分析婚姻状态与肿瘤特异性死亡（CSM）的关系。结果本次研究对象中，结婚组患者占62.1%，而从未结婚组和分居、离婚和丧偶（SDW）组分别为15.8和22.1%。多因素Logistic回归分析显示婚姻状态可能并不是影响肿瘤分期的因素（P＞0.05）。多因素Cox回归分析发现，相比于婚姻状况良好组，SDW （HR：1.194；P=0.005）组和未结婚组（HR：1.155, P=0.037）的CSM更高。结论婚姻状态可能并不是影响肿瘤分期的独立因素，但是婚姻状况不佳（未结婚和SDW）的病例CSM更高。
목적：탐토혼인상태여음경린상세포암（SCCP）환자적예후료효관계。방법이용SEER수거고1988년지2009년진단위SCCP적병례2681례。Logistic회귀분석혼인상태여종류분기적관계。Cox회귀분석혼인상태여종류특이성사망（CSM）적관계。결과본차연구대상중，결혼조환자점62.1%，이종미결혼조화분거、리혼화상우（SDW）조분별위15.8화22.1%。다인소Logistic회귀분석현시혼인상태가능병불시영향종류분기적인소（P＞0.05）。다인소Cox회귀분석발현，상비우혼인상황량호조，SDW （HR：1.194；P=0.005）조화미결혼조（HR：1.155, P=0.037）적CSM경고。결론혼인상태가능병불시영향종류분기적독립인소，단시혼인상황불가（미결혼화SDW）적병례CSM경고。
Objective To investigate the relationship between marital status and prognosis of patients with squamous cell carcinoma of the penis (SCCP). Methods 2681 SCCP patients between 1988 to 2009 who underwent primary tumor excision (PTE), registered in Surveillance, Epidemiology, and End Results (SEER) database, were retrospectively analyzed. Logistic regression analysis defined the relationship of marital status and tumor stage. Cox regression analysis determined the relationship between marital status and cancer-specific mortality (CSM). Results Of all patients, the majority (62.1%) were married. 22.1 and 15.5%patients were separated/divorced/widowed (SDW) and never married men, respectively. Multivariable Logistic models analysis showed that marital status had no effects on tumor stage (P>0.05). Multivariable Cox models analysis showed that the never married and SDW men had higher CSM rates (hazard ratio [HR]:1.194, P=0.005, HR:1.155, P=0.037, respectively) than married men. Conclusion Marital status might not be an independent risk factor for tumor stage. However, SDW and never married men had higher CSM rates than married men.