中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
4期
439-442
,共4页
孙勇%周晓芹%廖燚%王淑霞%张嫣
孫勇%週曉芹%廖燚%王淑霞%張嫣
손용%주효근%료일%왕숙하%장언
肥胖%原发性骨质疏松症%社区
肥胖%原髮性骨質疏鬆癥%社區
비반%원발성골질소송증%사구
Obesity%Primary osteoporosis%Community
目的：研究肥胖与原发性骨质疏松症的关联性。方法基于社区多级整群抽样的方法，获得2498例18岁以上居民的相关信息，通过HOLOGIC双能X线骨密度仪测定骨密度，通过分层及多因素logistic回归分析，对肥胖与原发性骨质疏松症的关联性进行研究。结果按照性别分层，男性人群中结果显示肥胖和原发性骨质疏松症呈负关联（χMH2＝26.845，P＜0.001），同时也可以看到Ⅱ度肥胖者的原发性骨质疏松症患病率要高于Ⅰ度肥胖者（11.1％＞6.6％）；女性人群中肥胖和原发性骨质疏松症的关联无统计学意义（χMH2＝2.007，P＝0.157）；如不分层，资料显示人群肥胖和原发性骨质疏松症呈负关联（χMH2＝7.016，P＝0.008）。按照年龄分层后，各年龄段（除age≥70组）均显示肥胖和原发性骨质疏松症呈负关联（χMH 2值依次为4.152、15.306、10.212、18.499、3.341，P值依次为0.042、＜0.001、0.001、＜0.001、0.068）。通过多因素logistic回归分析，调整性别、年龄后，结果显示肥胖和原发性骨质疏松症呈负关联（OR＝0.703，OR的95％C．I．为0.620～0.799）。结论骨质疏松症与肥胖有密切联系，体重管理在预防骨质疏松方面的作用是个公共健康问题，值得广泛关注。
目的：研究肥胖與原髮性骨質疏鬆癥的關聯性。方法基于社區多級整群抽樣的方法，穫得2498例18歲以上居民的相關信息，通過HOLOGIC雙能X線骨密度儀測定骨密度，通過分層及多因素logistic迴歸分析，對肥胖與原髮性骨質疏鬆癥的關聯性進行研究。結果按照性彆分層，男性人群中結果顯示肥胖和原髮性骨質疏鬆癥呈負關聯（χMH2＝26.845，P＜0.001），同時也可以看到Ⅱ度肥胖者的原髮性骨質疏鬆癥患病率要高于Ⅰ度肥胖者（11.1％＞6.6％）；女性人群中肥胖和原髮性骨質疏鬆癥的關聯無統計學意義（χMH2＝2.007，P＝0.157）；如不分層，資料顯示人群肥胖和原髮性骨質疏鬆癥呈負關聯（χMH2＝7.016，P＝0.008）。按照年齡分層後，各年齡段（除age≥70組）均顯示肥胖和原髮性骨質疏鬆癥呈負關聯（χMH 2值依次為4.152、15.306、10.212、18.499、3.341，P值依次為0.042、＜0.001、0.001、＜0.001、0.068）。通過多因素logistic迴歸分析，調整性彆、年齡後，結果顯示肥胖和原髮性骨質疏鬆癥呈負關聯（OR＝0.703，OR的95％C．I．為0.620～0.799）。結論骨質疏鬆癥與肥胖有密切聯繫，體重管理在預防骨質疏鬆方麵的作用是箇公共健康問題，值得廣汎關註。
목적：연구비반여원발성골질소송증적관련성。방법기우사구다급정군추양적방법，획득2498례18세이상거민적상관신식，통과HOLOGIC쌍능X선골밀도의측정골밀도，통과분층급다인소logistic회귀분석，대비반여원발성골질소송증적관련성진행연구。결과안조성별분층，남성인군중결과현시비반화원발성골질소송증정부관련（χMH2＝26.845，P＜0.001），동시야가이간도Ⅱ도비반자적원발성골질소송증환병솔요고우Ⅰ도비반자（11.1％＞6.6％）；녀성인군중비반화원발성골질소송증적관련무통계학의의（χMH2＝2.007，P＝0.157）；여불분층，자료현시인군비반화원발성골질소송증정부관련（χMH2＝7.016，P＝0.008）。안조년령분층후，각년령단（제age≥70조）균현시비반화원발성골질소송증정부관련（χMH 2치의차위4.152、15.306、10.212、18.499、3.341，P치의차위0.042、＜0.001、0.001、＜0.001、0.068）。통과다인소logistic회귀분석，조정성별、년령후，결과현시비반화원발성골질소송증정부관련（OR＝0.703，OR적95％C．I．위0.620～0.799）。결론골질소송증여비반유밀절련계，체중관리재예방골질소송방면적작용시개공공건강문제，치득엄범관주。
Objective To study the correlation between obesity and primary osteoporosis.Methods Adopting the multi-stage cluster sampling method based on community, the information of 2498 residents elder than 18 years old was obtained.The bone mineral density ( BMD) was measured using the HOLOGIC dual energy X-ray absorptiometry.The results were analyzed using stratification analysis and the multivariate logistic regression analysis, in order to investigate the correlation between obesity and primary osteoporosis.Results When stratified by sex, a negative correlation between obesity and primary osteoporosis was observed in males (χ2MH =26.845, P<0.001).Simultaneously, the prevalence of primary osteoporosis in subjects with II degree obese was higher than that in I degree obese (11.1% >6.6%).In females, no significant association between obesity and primary osteoporosis was observed (χ2MH =2.007, P=0.157).Without the stratification of gender, the data showed a negative correlation between obesity and primary osteoporosis (χ2MH =7.016,P=0.008).When stratified by age, each period ( except the age group over 70) showed that obesity and primary osteoporosis was negatively associated (χ2MH =4.152, 15.306, 10.212, 18.499, and 3.341, respectively; and P was 0.042, 0.001, 0.001, <0.001, and 0.068, respectively).Through the multivariate logistic regression analysis, after adjusting the gender and age, the results showed that obesity and primary osteoporosis was negatively associated (OR =0.703, 95%CI: 0.620 -0.799).Conclusion Osteoporosis is closely associated with obesity.Weight management is a public health problem in the prevention of osteoporosis, which should be paid more attention.
