中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2013年
3期
232-236
,共5页
潘颖%顾小妹%朱瑛%钟绍%朱文华
潘穎%顧小妹%硃瑛%鐘紹%硃文華
반영%고소매%주영%종소%주문화
2型糖尿病%人体成分分析仪%中心性肥胖
2型糖尿病%人體成分分析儀%中心性肥胖
2형당뇨병%인체성분분석의%중심성비반
Type 2 diabetes mellitus%Body composition%Central obesity
目的 了解2型糖尿病患者与正常人体内成分的差异,进一步探讨肥胖与2型糖尿病的关系.方法 随机选取80例2型糖尿病患者(糖尿病组)及80例健康体检者(对照组),分别进行人体成分分析,包括体脂肪、内脏脂肪区域、骨骼肌、腰臀比及蛋白质、矿物质含量等指标,同时测定糖尿病患者的血糖、血脂、胰岛素抵抗指数、糖化血红蛋白.结果 糖尿病组体脂肪[(19.68 ±6.78) kg]、体脂百分比[(29.87±8.04)％]、肥胖程度[(115.93 ±15.94)％]、内脏脂肪区域[(104.48 ±36.19) cm2]、体质量指数[(24.85±3.51) kg/m2]、胸围[(94.06±7.86) cm]、腰围[(85.18 ±9.50) cm]、腰臀比(0.90±0.05)均明显高于对照组[体脂肪:(17.31 ±5.55) kg、体脂百分比:(27.38±6.47)％、肥胖程度:(108.88±13.80)％、内脏脂肪区域:(85.44±44.04) cm2、体质量指数:(23.43 ±3.10) kg/m2、胸围:(91.11 ±7.52) cm、腰围:(80.79±8.17) cm、腰臀比(0.86 ±0.05)](t值分别为2.55、2.30、3.12、2.86、2.73、2.28、3.12、4.76,P均＜0.05),而体质量控制[(-7.01 ±7.49)kg]、肥胖控制[(-8.53 ±6.66)kg]、肌肉控制[(1.52±1.43) kg]均低于对照组[体质量控制:(-4.08 ±6.79)kg、肥胖控制:(-6.39±5.78) kg、肌肉控制:(2.31 ±2.09) kg(t值分别为-2.59、-2.17、-2.15,P均＜0.05).糖尿病组尿酸与体质量控制、肥胖控制呈负相关(r值分别为-0.43、-0.42,P均＜0.01),与内脏脂肪区域、体脂百分比、腰臀比、体质量指数、肥胖程度、胸围、腰围、体脂肪呈正相关(r值分别为0.32、0.31、0.40、0.36、0.36、0.31、0.42、0.42,P均＜0.05),甘油三酯与体质量控制、肥胖控制呈负相关(r值分别为-0.44、-0.41,P均＜0.01),与体脂百分比、腰臀比、体质量指数、肥胖程度、胸围、腰围、体脂肪呈正相关(r值分别为0.27、0.35、0.46、0.46、0.35、0.42、0.42,P均＜0.05).结论 2型糖尿病患者的体脂肪含量及体脂肪分布与健康人有显著差异,中心性肥胖可能与糖尿病发生存在一定关系.
目的 瞭解2型糖尿病患者與正常人體內成分的差異,進一步探討肥胖與2型糖尿病的關繫.方法 隨機選取80例2型糖尿病患者(糖尿病組)及80例健康體檢者(對照組),分彆進行人體成分分析,包括體脂肪、內髒脂肪區域、骨骼肌、腰臀比及蛋白質、礦物質含量等指標,同時測定糖尿病患者的血糖、血脂、胰島素牴抗指數、糖化血紅蛋白.結果 糖尿病組體脂肪[(19.68 ±6.78) kg]、體脂百分比[(29.87±8.04)％]、肥胖程度[(115.93 ±15.94)％]、內髒脂肪區域[(104.48 ±36.19) cm2]、體質量指數[(24.85±3.51) kg/m2]、胸圍[(94.06±7.86) cm]、腰圍[(85.18 ±9.50) cm]、腰臀比(0.90±0.05)均明顯高于對照組[體脂肪:(17.31 ±5.55) kg、體脂百分比:(27.38±6.47)％、肥胖程度:(108.88±13.80)％、內髒脂肪區域:(85.44±44.04) cm2、體質量指數:(23.43 ±3.10) kg/m2、胸圍:(91.11 ±7.52) cm、腰圍:(80.79±8.17) cm、腰臀比(0.86 ±0.05)](t值分彆為2.55、2.30、3.12、2.86、2.73、2.28、3.12、4.76,P均＜0.05),而體質量控製[(-7.01 ±7.49)kg]、肥胖控製[(-8.53 ±6.66)kg]、肌肉控製[(1.52±1.43) kg]均低于對照組[體質量控製:(-4.08 ±6.79)kg、肥胖控製:(-6.39±5.78) kg、肌肉控製:(2.31 ±2.09) kg(t值分彆為-2.59、-2.17、-2.15,P均＜0.05).糖尿病組尿痠與體質量控製、肥胖控製呈負相關(r值分彆為-0.43、-0.42,P均＜0.01),與內髒脂肪區域、體脂百分比、腰臀比、體質量指數、肥胖程度、胸圍、腰圍、體脂肪呈正相關(r值分彆為0.32、0.31、0.40、0.36、0.36、0.31、0.42、0.42,P均＜0.05),甘油三酯與體質量控製、肥胖控製呈負相關(r值分彆為-0.44、-0.41,P均＜0.01),與體脂百分比、腰臀比、體質量指數、肥胖程度、胸圍、腰圍、體脂肪呈正相關(r值分彆為0.27、0.35、0.46、0.46、0.35、0.42、0.42,P均＜0.05).結論 2型糖尿病患者的體脂肪含量及體脂肪分佈與健康人有顯著差異,中心性肥胖可能與糖尿病髮生存在一定關繫.
목적 료해2형당뇨병환자여정상인체내성분적차이,진일보탐토비반여2형당뇨병적관계.방법 수궤선취80례2형당뇨병환자(당뇨병조)급80례건강체검자(대조조),분별진행인체성분분석,포괄체지방、내장지방구역、골격기、요둔비급단백질、광물질함량등지표,동시측정당뇨병환자적혈당、혈지、이도소저항지수、당화혈홍단백.결과 당뇨병조체지방[(19.68 ±6.78) kg]、체지백분비[(29.87±8.04)％]、비반정도[(115.93 ±15.94)％]、내장지방구역[(104.48 ±36.19) cm2]、체질량지수[(24.85±3.51) kg/m2]、흉위[(94.06±7.86) cm]、요위[(85.18 ±9.50) cm]、요둔비(0.90±0.05)균명현고우대조조[체지방:(17.31 ±5.55) kg、체지백분비:(27.38±6.47)％、비반정도:(108.88±13.80)％、내장지방구역:(85.44±44.04) cm2、체질량지수:(23.43 ±3.10) kg/m2、흉위:(91.11 ±7.52) cm、요위:(80.79±8.17) cm、요둔비(0.86 ±0.05)](t치분별위2.55、2.30、3.12、2.86、2.73、2.28、3.12、4.76,P균＜0.05),이체질량공제[(-7.01 ±7.49)kg]、비반공제[(-8.53 ±6.66)kg]、기육공제[(1.52±1.43) kg]균저우대조조[체질량공제:(-4.08 ±6.79)kg、비반공제:(-6.39±5.78) kg、기육공제:(2.31 ±2.09) kg(t치분별위-2.59、-2.17、-2.15,P균＜0.05).당뇨병조뇨산여체질량공제、비반공제정부상관(r치분별위-0.43、-0.42,P균＜0.01),여내장지방구역、체지백분비、요둔비、체질량지수、비반정도、흉위、요위、체지방정정상관(r치분별위0.32、0.31、0.40、0.36、0.36、0.31、0.42、0.42,P균＜0.05),감유삼지여체질량공제、비반공제정부상관(r치분별위-0.44、-0.41,P균＜0.01),여체지백분비、요둔비、체질량지수、비반정도、흉위、요위、체지방정정상관(r치분별위0.27、0.35、0.46、0.46、0.35、0.42、0.42,P균＜0.05).결론 2형당뇨병환자적체지방함량급체지방분포여건강인유현저차이,중심성비반가능여당뇨병발생존재일정관계.
Objective To compare the body composition of diabetic and healthy subjects and to investigate the correlation between obesity and type 2 diabetes mellitus.Methods Body composition was analyzed in 80 type 2 diabetic patients (diabetes group) and 80 healthy subjects (control group) selected at random.They were measured for body fat mass,visceral fat area,sketedtal muscle mass,waist-hip ratio,the content of protein and mineral,etc.The blood glucose,blood fat,insulin resistance index (Homa-IR) and glycosylated hemoglobin(HbA1c) were also measured.Results The means of body fat mass((19.68 ± 6.78)kg),percent body fat ((29.87 ± 8.04) ％),obesity degree ((115.93 ± 15.94) ％),visceral fat area ((104.48 ± 36.19) cm2),Body mass index(BMI) ((24.85 ± 3.51) kg/m2),chest circumference ((94.06 ±7.86) cm),waist circumference ((85.18 ± 9.50) cm) and waist-hip ratio (0.90 ± 0.05) were significantly higher than the means of healthy subjects'weight control ((-4.08 ± 6.79) kg),body fat mass ((17.31 ± 5.55)kg),percent body fat ((27.38 ± 6.47)％),obesity degree((108.88 ± 13.80)％),visceral fat area ((85.44 ±44.04) cm2),BMI ((23.43 ± 3.10) kg/m2),chest circumference ((91.11 ± 7.52) cm),waist circumference ((80.79±8.17) cm) and waist-hip ratio (0.86 ± 0.05) (t=2.55,2.30,3.12,2.86,2.73,2.28,3.12 and 4.76 respectively;P ＜0.05),body mass control ((-7.01 ± 7.49) kg),obesity control ((-8.53 ± 6.66)kg),muscles control((1.52 ± 1.43) kg) were lower than control group:the body mass control((-4.08 ±6.79) kg),obesity control ((-6.39 ± 5.78) kg),muscles control ((2.31 ± 2.09) kg).The uric acid was negatively related to weight control and obesity control (r =-0.43,-0.42 ; P ＜ 0.01),and were positively related to visceral fat area,percent body fat,waist-hip ratio,BMI,obesity degree,chest circumference,waist circumference and body fat mass (r =0.32,0.31,0.40,0.36,0.36,0.31,0.42,0.42 ; P ＜ 0.05).The triglyceride was negatively related to weight control and obesity control (r =-0.44,-0.41 ;P ＜ 0.01),and were positive related to percent body fat,waist-hip ratio,BMI,obesity degree,chest circumference,waist circumference and body fat mass(r =0.27,0.35,0.46,0.46,0.35,0.42,0.42 ;P ＜ 0.05).Conclusion The body fat and fat distribution are significantly different between diabetic and healthy subjects.There may be some relationship between central obesity and diabetes.
