国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2011年
15期
1883-1884
,共2页
念珠菌%临床标本%药物敏感性
唸珠菌%臨床標本%藥物敏感性
념주균%림상표본%약물민감성
Candida%Clinical specimens%Drug sensitivity
目的 分析279株临床念珠菌的药物敏感性,以指导临床合理用药治疗真菌感染.方法 沙保弱培养基培养标本,用APIAUX20C真菌板条进行鉴定分型,用ATB药敏板条进行药敏实验.结果 分离的菌株对两性霉素B敏感率100%、其次是5-氟胞嘧啶除了白色念珠菌敏感率88.2%,其它念珠菌在100%.依曲康唑,氟康唑,依立康唑敏感率很低,都在32%以上.结论 两性霉素B、5-氟胞嘧啶为治疗念珠菌感染的首选用药.
目的 分析279株臨床唸珠菌的藥物敏感性,以指導臨床閤理用藥治療真菌感染.方法 沙保弱培養基培養標本,用APIAUX20C真菌闆條進行鑒定分型,用ATB藥敏闆條進行藥敏實驗.結果 分離的菌株對兩性黴素B敏感率100%、其次是5-氟胞嘧啶除瞭白色唸珠菌敏感率88.2%,其它唸珠菌在100%.依麯康唑,氟康唑,依立康唑敏感率很低,都在32%以上.結論 兩性黴素B、5-氟胞嘧啶為治療唸珠菌感染的首選用藥.
목적 분석279주림상념주균적약물민감성,이지도림상합리용약치료진균감염.방법 사보약배양기배양표본,용APIAUX20C진균판조진행감정분형,용ATB약민판조진행약민실험.결과 분리적균주대량성매소B민감솔100%、기차시5-불포밀정제료백색념주균민감솔88.2%,기타념주균재100%.의곡강서,불강서,의립강서민감솔흔저,도재32%이상.결론 량성매소B、5-불포밀정위치료념주균감염적수선용약.
Objective To instruct reasonable use of medications for fungal infections by analyzing the drug sensitivity of 279 clinical Candida isolates. Methods The Candida isolates were cultured with Sobouraud's bouillon and were then typed with the API AUX 20C fungi ID panel. Susceptibility testing was performed with ATB strips. Results The sensitivity of all the isolates to amphotericin B was 100%, and that of all the isolates except Candida albicans to 5-fluorocytosine was 100%; 88.2% of Candida albicans isolates were sensitive to 5-fluorocytosine. The sensitivity to itraconazole, fluconazole, or uniconazole was very low ( approximately 32% ). Conclusions Amphotericin B and 5-fluorocytosine are the first drug of choice for treating Candida infections.
