CAJ | 학술논문

目的：研究奥曲肽在腹部外科手术后的临床应用效果。方法以2010年6月-2013年6月在医院普外科行腹部手术治疗的140例患者为研究对象，随机分为奥曲肽组与对照组各70例，奥曲肽组于术后应用奥曲肽治疗，对照组用等量0.9%氯化钠溶液治疗作为对照，比较2组发生腹胀、腹痛的例数、患者恢复自主排气的时间及术后并发症的发生情况。结果奥曲肽组发生腹胀、腹痛的例数、恢复自主排气的时间、腹痛腹胀缓解时间均少于对照组，差异有统计学意义（P ﹤0.05）；发生术后出血、脓肿继发脓毒症、术后胰腺炎、胰瘘的患者人数均少于对照组，差异有统计学意义（P ﹤0.05）。结论奥曲肽应用于腹部外科手术后能明显改善患者的腹痛、腹胀，缩短肛门排气时间，有效预防术后并发症的发生，值得临床推广应用。
목적：연구오곡태재복부외과수술후적림상응용효과。방법이2010년6월-2013년6월재의원보외과행복부수술치료적140례환자위연구대상，수궤분위오곡태조여대조조각70례，오곡태조우술후응용오곡태치료，대조조용등량0.9%록화납용액치료작위대조，비교2조발생복창、복통적례수、환자회복자주배기적시간급술후병발증적발생정황。결과오곡태조발생복창、복통적례수、회복자주배기적시간、복통복창완해시간균소우대조조，차이유통계학의의（P ﹤0.05）；발생술후출혈、농종계발농독증、술후이선염、이루적환자인수균소우대조조，차이유통계학의의（P ﹤0.05）。결론오곡태응용우복부외과수술후능명현개선환자적복통、복창，축단항문배기시간，유효예방술후병발증적발생，치득림상추엄응용。
Objective To study the clinical application of octreotide after abdominal surgical operation. Methods From June 2010 to June 2013,140 patients underwent abdominal operation were randomly divided into octreotide group and control group,each of 70 cases. The octreotide group accepted octreotide treatment,while the control group received 0. 9% so-dium chloride solution treatment. The abdominal distention,abdominal pain cases,patients recover independent exhaust time and postoperative complications of 2 groups were compared. Results The abdominal distention,abdominal pain cases,patients recover independent exhaust time and postoperative complications in octreotide group were all less or shorter than that of the control group,the differences were statistically significant(P ﹤ 0. 05). The number of patients suffered from postoperative hem-orrhage,abscess secondary to sepsis,postoperative pancreatitis,pancreatic fistula were less than that of the control group,the differences were statistically significant(P ﹤ 0. 05). Conclusion Octreotide used in abdominal operation can significantly im-prove the patient's abdominal pain,abdominal distension,shorten the time of anal exhaust,effectively prevent the occurrence of postoperative complications,which is worthy of clinical application.