CAJ | 학술논문

目的探讨动态监测老年吸入性肺炎患者血清超敏C反应蛋白(hs-CRP)水平的临床意义.方法选择50例老年吸入性肺炎患者,在确诊第1天、第3天和第7天检测患者血清hs-CRP水平,并根据患者的病情及预后进行分析和比较.结果 50例老年吸入性肺炎患者经积极治疗后,治愈或明显缓解37例,死亡13例(26.0％)；确诊第3天血清hs-CRP水平较第1天显著升高(P＜0.01),第7天较第3天回落明显(P＜0.01)；第3天和第7天患者血清hs-CRP水平在病情危重组均明显高于病情较轻组(P＜0.01)；不同时间点死亡组患者血清hs-CRP水平均明显高于治愈或好转组(P＜0.05或P＜0.01).结论动态监测血清hs-CRP水平的变化可有效反映老年吸入性肺炎患者的病情变化,并对病情及预后判断具有重要意义.
목적 탐토동태감측노년흡입성폐염환자혈청초민C반응단백(hs-CRP)수평적림상의의.방법 선택50례노년흡입성폐염환자,재학진제1천、제3천화제7천검측환자혈청hs-CRP수평,병근거환자적병정급예후진행분석화비교.결과 50례노년흡입성폐염환자경적겁치료후,치유혹명현완해37례,사망13례(26.0％)；학진제3천혈청hs-CRP수평교제1천현저승고(P＜0.01),제7천교제3천회락명현(P＜0.01)；제3천화제7천환자혈청hs-CRP수평재병정위중조균명현고우병정교경조(P＜0.01)；불동시간점사망조환자혈청hs-CRP수평균명현고우치유혹호전조(P＜0.05혹P＜0.01).결론 동태감측혈청hs-CRP수평적변화가유효반영노년흡입성폐염환자적병정변화,병대병정급예후판단구유중요의의.
Objective To study the value of monitoring high-sensitivity C-reactive protein (hs-CRP) in elderly patients with aspiration pneumonia.Methods 50 elderly patients with aspiration pneumonia were studied.The hs-CRP level was detected on the first day,the third day,and the seventh day of diagnosis,analyzed and compared combined with the patients' condition changes and outcomes.Results After the treatment,in 50 elderly patients with aspiration pneumonia,37 cases were cured or relieved,13 patients died (26.0 ％).On the third day,the hs-CRP level was significantly increased (P ＜0.01),and on the seventh day,the hs-CRP level was decreased significantly (P ＜0.01).On the third and seventh day,the hs-CRP level in the severe group was significantly higher than that in mild group (P ＜0.01).On different day,the hs-CRP level in death group was higher than that in cure or remission group (P ＜0.05 or P ＜0.01).Conclusions Dynamic monitoring of the changes of serum hs-CRP can effectively reflect the changes in the condition of elderly patients with aspiration pneumonia,the disease severity,and outcome prognosis.