CAJ | 학술논문

用沙棘叶、果、茎、根的提取物和籽油，对患H22和EAC的实体瘤小鼠进行灌胃实验。结果表明，沙棘不同器官提取物和籽油都具有显著的抑瘤效果。在15个不同处理剂量组中，有10个剂量组的抑瘤率都超过了30％，占到处理总数的66．6％。沙棘不同器官提取物对实体瘤小鼠的抑瘤率表现为：叶〉果〉油〉茎〉根，叶和果的高剂量组抑瘤率分别为58％和46．7％。沙棘提取物抑瘤的主要原因是增强了实体瘤小鼠的免疫功能，提高了脾指数和胸腺指数，且胸腺指数效果大于脾指数的。沙棘提取物有利于调节患病小鼠的脏器活力。
용사극협、과、경、근적제취물화자유，대환H22화EAC적실체류소서진행관위실험。결과표명，사극불동기관제취물화자유도구유현저적억류효과。재15개불동처리제량조중，유10개제량조적억류솔도초과료30％，점도처리총수적66．6％。사극불동기관제취물대실체류소서적억류솔표현위：협〉과〉유〉경〉근，협화과적고제량조억류솔분별위58％화46．7％。사극제취물억류적주요원인시증강료실체류소서적면역공능，제고료비지수화흉선지수，차흉선지수효과대우비지수적。사극제취물유리우조절환병소서적장기활력。
The seed oil and extractives from seabuckthorn leaves, fruits, stems and roots are irrigated into the stomachs of solid tumour mice with H22 and EAC, which all have significant inhibitory effect. Among fifteen different treatment doses of groups, ten groups of inhibitory tumor ratio are more than 30.0%, accounts for 66.6% of the total number. Inhibitory tumor ratio of seed oil and extractives from seabuckthorn organs are leaves〉 fruits〉 oil 〉stems 〉 roots, high doses of extractives from leaves and fruits were 58.00% and 46.69% respectively. The main reason why seabuck- thorn extract inhibits tumors is to better solid tumors of the mice immune function, improve the spleen index and the thymus index, and the thymus index greater than the effect of spleen index. Seabuckthorn extracts are propitious to adjust mice vigor.