生命科学仪器
生命科學儀器
생명과학의기
LIFE SCIENCES INSTRUMENT
2012年
5期
31-33
,共3页
液体顶空气相色谱法%大口径毛细管柱%有机溶剂残留%蒿甲醚
液體頂空氣相色譜法%大口徑毛細管柱%有機溶劑殘留%蒿甲醚
액체정공기상색보법%대구경모세관주%유궤용제잔류%호갑미
Solution headspace gas chromatography%Wide bore capillary column%Residual organic solvent%Artemether
建立了液体顶空气相色谱法测定蒿甲醚中有机溶剂残留量。采用DB-1大口径毛细管柱，以对照品作外标进行定量。甲醇、乙醇及二氯甲烷的线性范围分别为30．2～635．2μg·mL^-1（r=0．9991），6．4～64．5μg·mL^-1（r=0．9991）和5．5～68．7μg·mL^-1（r=0．9990）；回收率分别为99．9％，103．8％7f[199．3％；检测限分别为0．02μg·g^-1,0．04μg·g^-1和0．01μg·g^-1。本方法简单、准确、灵敏度及重现性好。
建立瞭液體頂空氣相色譜法測定蒿甲醚中有機溶劑殘留量。採用DB-1大口徑毛細管柱，以對照品作外標進行定量。甲醇、乙醇及二氯甲烷的線性範圍分彆為30．2～635．2μg·mL^-1（r=0．9991），6．4～64．5μg·mL^-1（r=0．9991）和5．5～68．7μg·mL^-1（r=0．9990）；迴收率分彆為99．9％，103．8％7f[199．3％；檢測限分彆為0．02μg·g^-1,0．04μg·g^-1和0．01μg·g^-1。本方法簡單、準確、靈敏度及重現性好。
건립료액체정공기상색보법측정호갑미중유궤용제잔류량。채용DB-1대구경모세관주，이대조품작외표진행정량。갑순、을순급이록갑완적선성범위분별위30．2～635．2μg·mL^-1（r=0．9991），6．4～64．5μg·mL^-1（r=0．9991）화5．5～68．7μg·mL^-1（r=0．9990）；회수솔분별위99．9％，103．8％7f[199．3％；검측한분별위0．02μg·g^-1,0．04μg·g^-1화0．01μg·g^-1。본방법간단、준학、령민도급중현성호。
A solution headspace gas chromatography for the determination of residual organic solvent in Artemether was established. A DB-1 wide bore capillary column was used with Referencel standard.The linear range for methanol, ethanol and dichloromethane were 30.2-635.2 μg·mL^-1(r=0.9991), 6.4-64.5 μg·mL^-1 (r=0.9991) and 5.5-68.7 μg·mL^-1 (r=0.9990) respectively. The average recoveries of methanol, ethanol and diehloromethane were 99.9%, 103.8%and 99.3%respectively. The lowest test limits of methanol , ethanol and dichloromethane were 0.02 μg·g^-1, 0.04 μg·g^-1 and 0.01 μg·g^-1 ,respectively. The method was simple, accurate, sensitive and repeatable.
