CAJ | 학술논문

目的：了解发生中药药源性疾病患者一般资料、药品名称、用法用量、给药途径、主要临床表现、转归等。方法收集2004-2012年东营地区（东营市药品不良反应监测中心提供数据）中药及制剂导致的药源性疾病进行回顾性分析。结果中药及制剂导致的药源性疾病共计3446例，共涉及603种中药，包括中药制剂599种，中药饮片4种。新的、严重的药品不良反应发生率高。结论急需建立中药制剂致药源性疾病的防御体系，对中药药源性疾病进行系统的资料收集、监测和分析，并通过有效途径及管理措施为临床医生提供合理用药信息及咨询服务，为药品管理行政部门提供修改说明书的依据，最大限度降低药源性疾病的发生，维护公众用药安全。
목적：료해발생중약약원성질병환자일반자료、약품명칭、용법용량、급약도경、주요림상표현、전귀등。방법수집2004-2012년동영지구（동영시약품불량반응감측중심제공수거）중약급제제도치적약원성질병진행회고성분석。결과중약급제제도치적약원성질병공계3446례，공섭급603충중약，포괄중약제제599충，중약음편4충。신적、엄중적약품불량반응발생솔고。결론급수건립중약제제치약원성질병적방어체계，대중약약원성질병진행계통적자료수집、감측화분석，병통과유효도경급관리조시위림상의생제공합리용약신식급자순복무，위약품관리행정부문제공수개설명서적의거，최대한도강저약원성질병적발생，유호공음용약안전。
Objective To find out the general features ,drug type ,route of administration DID clinical mani-festation,outcome and so on in DID patients .Methods The statements of drug-induced diseases caused by traditional Chinese medicine and its preparation were collected ( the data provided by Adverse Drug Reaction Monitoring Center of Dongying City ) from 2004 to 2012 in Dongying area ,which would be reviewed and analyzed .Results 3 446 drug-induced disease cases of traditional Chinese medicine preparations were screened out .From 3 446 DID reports in which 603 kinds were involved ,599 kinds of traditional Chinese medicine and 4 kinds of Chinese herbal medicine .The rates of the new and serious DID were high .Conclusion The defense system of the drug-induced diseases caused by traditional Chinese medicine need to be established urgently which is used for collecting ,monitoring and analyzing the data of Chinese medicine drugs to the clinicians ,providing the information of rational use and advisory services by ef-fective ways and management measures ,and providing the basis to modify the specification for pharmaceutical manage-ment and administrative departments .As a result,it can minimize the incidence of drug-induced diseases and maintain the safety of the public takeing medicine .