CAJ | 학술논문

x针对海洋水产品腹泻性毒素检测问题，设计了一种新型的基于细胞阻抗传感器( ECIS)的毒素快速检测分析系统。相对于传统的毒素检测方法，该系统具有操作简便，高一致性和高通量等特点。介绍了系统的硬件设计和软件设计，通过对系统整体性能测试以及使用神经母细胞瘤细胞(Neuro-2a)对腹泻性贝毒(DSP)大田软海绵酸(OA)进行毒性检测实验，用以验证系统平台的可行性。实验结果表明，基于细胞传感器的海洋水产品腹泻性毒性检测系统具备快速，长期，无损和高通量测量的特点，为腹泻性毒素检测提供了新的平台。
x침대해양수산품복사성독소검측문제，설계료일충신형적기우세포조항전감기( ECIS)적독소쾌속검측분석계통。상대우전통적독소검측방법，해계통구유조작간편，고일치성화고통량등특점。개소료계통적경건설계화연건설계，통과대계통정체성능측시이급사용신경모세포류세포(Neuro-2a)대복사성패독(DSP)대전연해면산(OA)진행독성검측실험，용이험증계통평태적가행성。실험결과표명，기우세포전감기적해양수산품복사성독성검측계통구비쾌속，장기，무손화고통량측량적특점，위복사성독소검측제공료신적평태。
A novel system for fast poison detection based on electrical cell-substrate impedance sensing was proposed and fabricated for resolving the problems of marine diarrheic shellfish poison detection. Comparing with tranditional methods,the system has the performance of simple operation,high consistency and high throughput. In this study,the design of system hardware and software were introduced and then its performance was tested. Finally, toxin detection experiments with Neuro-2a,DSP and OA were used to certify the availability of system. The results showed that the system had some attributes such as fast,long-time monitoring,no invasion and high throughput and applied a new detection platform for DSP of marine productions.