CAJ | 학술논문

目的分析1例确诊人感染H7N9禽流感重症患者临床和流行病学特点,并对治疗方法进行探讨.方法对该患者的临床、流行病学资料、实验室检查、影像学资料进行回顾性分析.结果该患者为55岁男性,从事活禽贩卖及宰杀职业,以咳嗽、咳黄脓痰、发热为首发症状,病程早期出现胸闷、呼吸困难及痰中带血,无明显上呼吸道症状；实验室检查:血白细胞、淋巴细胞及中性粒细胞计数降低,血乳酸脱氢酶及超敏C反应蛋白增高.胸部CT显示双肺炎,右肺为主；短期内病灶进展快,出现急性肺损伤.给予氧疗、奥司他韦、抗感染药物、激素、免疫球蛋白等治疗.结论人感染H7N9禽流感临床进展快,以肺部损伤为主,与接触活禽有关.
목적 분석1례학진인감염H7N9금류감중증환자림상화류행병학특점,병대치료방법진행탐토.방법 대해환자적림상、류행병학자료、실험실검사、영상학자료진행회고성분석.결과 해환자위55세남성,종사활금판매급재살직업,이해수、해황농담、발열위수발증상,병정조기출현흉민、호흡곤난급담중대혈,무명현상호흡도증상；실험실검사:혈백세포、림파세포급중성립세포계수강저,혈유산탈경매급초민C반응단백증고.흉부CT현시쌍폐염,우폐위주；단기내병조진전쾌,출현급성폐손상.급여양료、오사타위、항감염약물、격소、면역구단백등치료.결론 인감염H7N9금류감림상진전쾌,이폐부손상위주,여접촉활금유관.
Objective To analyze the clinical features,epidemiologic information,and outcome in a confirmed case of human infection with influenza A (H7N9).Methods Clinical data on vital signs,physical findings,laboratory tests,chest CT scan,and epidemiologic data were retrospectively analyzed.Results The patient was a poultry worker aged 55 years old and resided in a town.He had initial symptoms of cough,fever,rapid progression,and significant hypoxemia.Laboratory tests showed decreased leukocytes,increased lactate dehydrogenase and hypersensitive C-reactive protein.Chest CT scan showed bilateral pulmonary infection,especially in the right lung.The patient developed acute lung injury.Oseltamivir,anti-infective drugs,immunoglobulin,and oxygen therapy were administered.Conclusions Charicteristics of avian influenza A (H7N9) infection in human include rapid deterioration,pulmonary involvement,and poultry contact.