体育科研
體育科研
체육과연
SPORTS SCIENCE RESEARCH
2012年
2期
75-78,100
,共5页
COMT(Catechol-O-Methyltransferase)%视觉%P3%工作记忆
COMT(Catechol-O-Methyltransferase)%視覺%P3%工作記憶
COMT(Catechol-O-Methyltransferase)%시각%P3%공작기억
COMT(Catechol-O-Methyl-transferase)%visual%P3%working memory
针对不同COMT基因型的被试者,首次利用视觉事件相关电位P3来观测被试者在长时间心算任务中COMT基因多态型与脑皮层电生理的关系。选取20名不同基因型人员作为被试者,在执行9组不同难度的心算任务后即刻,进行5 min的3-back任务,探讨健康成人数字工作记忆能力变化情况。Val/Val基因型的被试者P3波幅显著高于Val/Met基因型（P〈0.01）,但和Met/Met基因型被试者的波幅无差异;Val/Met基因型被试者在不同的工作记忆任务中都显示了最差的成绩。
針對不同COMT基因型的被試者,首次利用視覺事件相關電位P3來觀測被試者在長時間心算任務中COMT基因多態型與腦皮層電生理的關繫。選取20名不同基因型人員作為被試者,在執行9組不同難度的心算任務後即刻,進行5 min的3-back任務,探討健康成人數字工作記憶能力變化情況。Val/Val基因型的被試者P3波幅顯著高于Val/Met基因型（P〈0.01）,但和Met/Met基因型被試者的波幅無差異;Val/Met基因型被試者在不同的工作記憶任務中都顯示瞭最差的成績。
침대불동COMT기인형적피시자,수차이용시각사건상관전위P3래관측피시자재장시간심산임무중COMT기인다태형여뇌피층전생리적관계。선취20명불동기인형인원작위피시자,재집행9조불동난도적심산임무후즉각,진행5 min적3-back임무,탐토건강성인수자공작기억능력변화정황。Val/Val기인형적피시자P3파폭현저고우Val/Met기인형（P〈0.01）,단화Met/Met기인형피시자적파폭무차이;Val/Met기인형피시자재불동적공작기억임무중도현시료최차적성적。
It was the first to use P3 visual event-related potentials to explore the relationships between COMT polymorphism and cortical physiology in mental arithmetic tasks for a long time.20 different genotype subjects were chosen for 9-group mental arithmetic work of different workload,followed immedi-ately by 5 minutes＇ 3-back task so as to observe the changes of numerical working memory ability of healthy adults.P3 amplitude of the subjects with Val/Val homozygote is significantly higher than the subjects with Val/Met homozygote（P0.01）.But compared to the subjects with Met/Met homozygote,there is no distinct significance in P3 amplitude.Val/Met heterozygous individuals show poorer performance compared to those with other genotypes.
