中国牛业科学
中國牛業科學
중국우업과학
CHINA CATTLE SCIENCE
2012年
2期
36-39
,共4页
高晓猛%张春雷%房兴堂%陈宏
高曉猛%張春雷%房興堂%陳宏
고효맹%장춘뢰%방흥당%진굉
grbl4基因%GRBl4蛋白功能%研究进展
grbl4基因%GRBl4蛋白功能%研究進展
grbl4기인%GRBl4단백공능%연구진전
grb14 gene%GRB14 protein function%research progress
鉴于growthfactorreceptor—boundprotein14（GRBl4）在胰岛素信号和纤维母细胞生长因子（fibroblastgrowthfactor，FGF）信号调节上的重要作用。研究表明GRBl4与脊椎动物的生长发育有着密切的联系。近年来，该基因已经成为调控胰岛素信号和FGF信号途径的研究热点，但在牛上还未见报道。在此，本文对牛grbl4基因的功能及其相应机理进行了综述。
鑒于growthfactorreceptor—boundprotein14（GRBl4）在胰島素信號和纖維母細胞生長因子（fibroblastgrowthfactor，FGF）信號調節上的重要作用。研究錶明GRBl4與脊椎動物的生長髮育有著密切的聯繫。近年來，該基因已經成為調控胰島素信號和FGF信號途徑的研究熱點，但在牛上還未見報道。在此，本文對牛grbl4基因的功能及其相應機理進行瞭綜述。
감우growthfactorreceptor—boundprotein14（GRBl4）재이도소신호화섬유모세포생장인자（fibroblastgrowthfactor，FGF）신호조절상적중요작용。연구표명GRBl4여척추동물적생장발육유착밀절적련계。근년래，해기인이경성위조공이도소신호화FGF신호도경적연구열점，단재우상환미견보도。재차，본문대우grbl4기인적공능급기상응궤리진행료종술。
Growth factor receptor bound protein 14（GRB14）played an important role in regulatiing insulin signaling and fibroblast growth factor signaling. It had been reported that GRB14 had great correlation with growth and development of vertebrate. In recent years, grb14 has become popular in researches of regulating insulin and fibroblast growth factor signaling. But it had not been reported in cattle. The functions and its corresponding mechanism, were summarized in this paper.
