CAJ | 학술논문

良性气道狭窄是呼吸介入领域的常见疾病,创伤性因素是气道狭窄形成的主要病因之一.建立气道狭窄动物模型对深入研究其发病机制与疾病防治具有主要意义.目前已有不少通过损伤气管壁的方法建立气道狭窄动物模型的研究报道.本文从实验动物、周期、方法及展望等方面,就建立创伤性气道狭窄动物模型的现状与研究进展作一综述.
량성기도협착시호흡개입영역적상견질병,창상성인소시기도협착형성적주요병인지일.건립기도협착동물모형대심입연구기발병궤제여질병방치구유주요의의.목전이유불소통과손상기관벽적방법건립기도협착동물모형적연구보도.본문종실험동물、주기、방법급전망등방면,취건립창상성기도협착동물모형적현상여연구진전작일종술.
Benign tracheal stenosis is a common disease in interventional pulmonology,which is mainly resulted from exogenous trauma.The establishment of animal models is helpful to study the pathogenesis and treatment of benign tracheal stenosis.Recent studies have been introduced many methods of traumatic tracheal stenosis.This paper reviews the establishment of animal models with tracheal stenosis,based on different animals,experimental period,methods,and research prospect.