大理学院学报：综合版
大理學院學報：綜閤版
대이학원학보：종합판
Journal of Dali University
2012年
9期
95-97
,共3页
李胜囡%韩本序%刘圣旭%肖培云
李勝囡%韓本序%劉聖旭%肖培雲
리성닙%한본서%류골욱%초배운
RP-HPLC%桑姜感冒胶囊%绿原酸
RP-HPLC%桑薑感冒膠囊%綠原痠
RP-HPLC%상강감모효낭%록원산
RP-HPLC%Sangjiangganmao capsules%chlorogenic acid
目的：测定桑姜感冒胶囊中绿原酸的含量。方法：采用Agela XBP-C18色谱柱（250 mm×4.6 mm,5μm）,以乙腈-0.4%磷酸（9∶91）为流动相,检测波长327 nm,流速1.0 mL/min。结果：绿原酸进样量在0.02~0.25μg范围内有良好的线性关系,r=0.9998,平均加样回收率为99.5%,RSD为0.67%（n=6）。结论：本方法操作简便、结果准确、灵敏度高、重复性好,可作为桑姜感冒胶囊中绿原酸的含量测定方法。
目的：測定桑薑感冒膠囊中綠原痠的含量。方法：採用Agela XBP-C18色譜柱（250 mm×4.6 mm,5μm）,以乙腈-0.4%燐痠（9∶91）為流動相,檢測波長327 nm,流速1.0 mL/min。結果：綠原痠進樣量在0.02~0.25μg範圍內有良好的線性關繫,r=0.9998,平均加樣迴收率為99.5%,RSD為0.67%（n=6）。結論：本方法操作簡便、結果準確、靈敏度高、重複性好,可作為桑薑感冒膠囊中綠原痠的含量測定方法。
목적：측정상강감모효낭중록원산적함량。방법：채용Agela XBP-C18색보주（250 mm×4.6 mm,5μm）,이을정-0.4%린산（9∶91）위류동상,검측파장327 nm,류속1.0 mL/min。결과：록원산진양량재0.02~0.25μg범위내유량호적선성관계,r=0.9998,평균가양회수솔위99.5%,RSD위0.67%（n=6）。결론：본방법조작간편、결과준학、령민도고、중복성호,가작위상강감모효낭중록원산적함량측정방법。
Objective: To establish a RP-HPLC method for the determination of chlorogenic acid in Sangjiangganmao capsules. Methods: An Agela XBP-C18(250 mm×4.6 mm,5 μm) column was applied,the mobile phase was acetonitrile-0.4% phosphoric(9:91),the detection wavelength was 327 nm with the flow rate of 0.1mL/min.Results: There was a good linear relationship in the chlorogenic acid concentration range of 0.02-0.25 μg(r=0.999 8).The average recovery was 99.5%,RSD=0.67%(n=6).Conclusion: The method was with good repeatability,flexibility and high sensitivity,which can be used in the quality control of Sangjiangganmao capsules.
